Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6061462 | 0.83 | SIGMAR1 (0.32) | SIGMAR1 | |
| SCHEMBL1921591 | 0.75 | HTR2A (0.38) | SIGMAR1HTR6HTR2A | |
| Hydrochloric Acid SCHEMBL4479517 | 0.74 | HTR2A (0.35) | SIGMAR1HTR6HTR2A | |
| SCHEMBL30084485 | 0.74 | SIGMAR1 (0.38) | SIGMAR1HTR6HTR2A | |
| SCHEMBL9860034 | 0.74 | HTR2A (0.37) | SIGMAR1HTR6HTR2A | |
| SCHEMBL5034593 | 0.74 | SIGMAR1 (0.38) | SIGMAR1HTR6HTR2A | |
| Hydrochloric Acid SCHEMBL6061999 | 0.74 | HTR6 (0.39) | SIGMAR1HTR6HTR2A | |
| SCHEMBL11623231 | 0.72 | HTR2A (0.36) | SIGMAR1HTR6HTR2A | |
| SCHEMBL30530453 | 0.72 | HTR2A (0.36) | SIGMAR1HTR6HTR2A | |
| SCHEMBL4466071 | 0.72 | HTR2A (0.36) | SIGMAR1HTR6HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060142147-A1 | Catalysts compositions for the polymerization and copolymerization of alpha-olefins | REPSOL QUIMICA, S.A. (ES) | 2006-06-29 | — | — | US | claimed |
| US-20060142147-A1 | Catalysts compositions for the polymerization and copolymerization of alpha-olefins | REPSOL QUIMICA, S.A. (ES) | 2006-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142147-A1 | Catalysts compositions for the polymerization and copolymerization of alpha-olefins | B2M, OPRM1, POLM | SIGMAR1 704/4885HTR6 1387/4885HTR2A 3334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.