Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6061464 | 0.83 | HTR6 (0.37) | HTR6SIGMAR1HTR2A | |
| SCHEMBL4469498 | 0.78 | HTR6 (0.39) | HTR6SIGMAR1HTR2A | |
| SCHEMBL846366 | 0.78 | RET (0.37) | HTR6SIGMAR1HTR2A | |
| Hydrochloric Acid SCHEMBL7107235 | 0.74 | SIGMAR1 (0.35) | HTR6SIGMAR1HTR2A | |
| SCHEMBL4480045 | 0.74 | HTR6 (0.43) | HTR6SIGMAR1HTR2A | |
| SCHEMBL6061548 | 0.73 | HTR6 (0.38) | HTR6SIGMAR1HTR2A | |
| SCHEMBL439955 | 0.73 | HTR2A (0.35) | HTR6SIGMAR1HTR2A | |
| SCHEMBL6061490 | 0.73 | HTR6 (0.35) | HTR6SIGMAR1 | |
| SCHEMBL7899799 | 0.73 | HTR6 (0.33) | HTR6SIGMAR1HTR2A | |
| SCHEMBL28440009 | 0.73 | HTR2A (0.37) | HTR6SIGMAR1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060142147-A1 | Catalysts compositions for the polymerization and copolymerization of alpha-olefins | REPSOL QUIMICA, S.A. (ES) | 2006-06-29 | — | — | US | claimed |
| US-20060142147-A1 | Catalysts compositions for the polymerization and copolymerization of alpha-olefins | REPSOL QUIMICA, S.A. (ES) | 2006-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142147-A1 | Catalysts compositions for the polymerization and copolymerization of alpha-olefins | B2M, OPRM1, POLM | HTR6 1387/4885SIGMAR1 704/4885HTR2A 3334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.