Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 6/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6064466 | 0.83 | POLB (0.40) | POLBTDP1KMT2ABCHEACHE | |
| SCHEMBL26177667 | 0.79 | POLB (0.46) | POLBTDP1KMT2ABCHEACHE | |
| SCHEMBL6064191 | 0.77 | POLB (0.41) | POLBTDP1KMT2ABCHEACHE | |
| SCHEMBL3365928 | 0.77 | NFE2L2 (0.44) | TDP1KMT2AGSK3BMAPK1HTT | |
| SCHEMBL3362703 | 0.77 | MEN1 (0.49) | POLBKMT2ATSHRMAPK1GAA | |
| SCHEMBL28629683 | 0.71 | SLC6A2 (0.49) | POLBGSK3BALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL238021 | 0.70 | KDM4E (0.50) | TDP1KMT2ACYP3A4MAPK1GAA | |
| SCHEMBL3203530 | 0.70 | SMN1; SMN2 (0.48) | BCHEACHEMAOBCYP3A4TSHR | |
| SCHEMBL29350418 | 0.70 | KDM4E (0.50) | TDP1KMT2ACYP3A4MAPK1GAA | |
| SCHEMBL1259480 | 0.70 | GAA (0.40) | POLBTDP1KMT2ABCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7019166-B2 | Method for the production of 2,4,5-trimethylphenyl acetic acid | BAYER CROPSCIENCE AG (DE) | 2006-03-28 | — | — | US | disclosed |
| US-20050182274-A1 | Method for the production of 2,4,5-trimethylphenyl acetic acid | BAYER CROPSCIENCE AG (DE) | 2005-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182274-A1 | Method for the production of 2,4,5-trimethylphenyl acetic acid | CA6, DDC, HACL2 | POLB 3844/4885TDP1 4225/4885KMT2A 184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.