SCHEMBL6064641

SCHEMBL6064641

C=C(C)C(=O)OCCNC(N)=S

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.46
TSHR P16473 4/20 0.44
ALDH1A1 P00352 4/20 0.39
TDP1 Q9NUW8 2/20 0.35
POLB P06746 1/20 0.35
APEX1 P27695 1/20 0.35
HTT P42858 1/20 0.35
TAS2R38 P59533 1/20 0.33
KMT2A Q03164 3/20 0.31
MEN1 O00255 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
HPGD P15428 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8358232 0.90 TSHR (0.50) THRBTSHRALDH1A1TDP1POLB
SCHEMBL30484793 0.87 TSHR (0.56) THRBTSHRTDP1POLBAPEX1
SCHEMBL23943854 0.85 THRB (0.40) THRBTSHRALDH1A1TDP1POLB
SCHEMBL491194 0.85 THRB (0.48) THRBTSHRALDH1A1TDP1POLB
Hydrochloric Acid SCHEMBL27901132 0.84 THRB (0.47) THRBTSHRALDH1A1TDP1POLB
SCHEMBL28456926 0.82 THRB (0.46) THRBTSHRALDH1A1TDP1POLB
SCHEMBL24099887 0.82 THRB (0.46) THRBTSHRALDH1A1TDP1POLB
SCHEMBL12808628 0.81 THRB (0.52) THRBTSHRALDH1A1TDP1POLB
SCHEMBL685408 0.81 THRB (0.52) THRBTSHRALDH1A1TDP1POLB
SCHEMBL2195083 0.81 THRB (0.52) THRBTSHRALDH1A1TDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035564-A1 CROSSLINKABLE POLYSILOXANE COMMW SCIENT IND RES ORG (AU) 2026-02-05 US disclosed
US-12528940-B2 Crosslinkable polysiloxane COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2026-01-20 US disclosed
US-20230091115-A1 CROSSLINKABLE POLYSILOXANE COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2023-03-23 US disclosed
US-20220380553-A1 CROSSLINKABLE POLYSILOXANE COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2022-12-01 US disclosed
EP-4093807-A1 CROSSLINKABLE POLYSILOXANE Commonwealth Scientific and Industrial Research Organisation (AU) 2022-11-30 EP disclosed
CN-115066457-A Crosslinkable polysiloxanes 联邦科学和工业研究组织 2022-09-16 CN disclosed
US-20060165638-A1 Compositions comprising at least one copolymer (a) and at least one copolymer (b) and use thereof in cosmetic preparations BASF AKTIENGESELLSCHAFT (DE) 2006-07-27 US disclosed
US-5244995-A Vinyl halide aqueous polymerization dispersant system THE BF GOODRICH COMPANY (US) 1993-09-14 US disclosed
US-5155189-A Derived from repeating units of acrylic and/or methacrylic ester polymers THE B. F. GOODRICH COMPANY (US) 1992-10-13 US disclosed
EP-0483051-A1 Improved vinyl halide aqueous polymerization dispersant system The Geon Company (US) 1992-04-29 EP disclosed
US-4190693-A WATERBASE, THERMOSETTING RESINS FOR DIRECT ROLL COATING ROHM AND HAAS COMPANY (US) 1980-02-26 US disclosed
US-4126595-A Aqueous coating compositions comprising acrylic oligomers, high molecular weight polymers and crosslinkers ROHM AND HAAS COMPANY (US) 1978-11-21 US disclosed
US-4087397-A Aqueous coating compositions comprising acrylic oligomers and high molecular weight polymers ROHM AND HAAS COMPANY (US) 1978-05-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035564-A1 CROSSLINKABLE POLYSILOXANE EPCAM, ITGB4, ITGB3 THRB 912/4885TSHR 1296/4885ALDH1A1 596/4885
US-12528940-B2 Crosslinkable polysiloxane EIF2S1, SSR4, MSR1 THRB 1502/4885TSHR 775/4885ALDH1A1 1550/4885
US-20060165638-A1 Compositions comprising at least one copolymer (a) and at least one copolymer (b) and use thereof in cosmetic preparations CBR1, OXER1, OXGR1 THRB 1107/4885TSHR 516/4885ALDH1A1 1193/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.