Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP7 | P09237 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3171895 | 0.86 | FPR2 (0.34) | MMP1MMP3MMP7FPR2 | |
| SCHEMBL6747811 | 0.78 | FPR2 (0.40) | MMP1MMP3MMP7FPR2 | |
| SCHEMBL6697299 | 0.74 | F2RL1 (0.34) | — | |
| SCHEMBL2776439 | 0.66 | ALOX15 (0.38) | — | |
| SCHEMBL31149401 | 0.62 | ADRA2A (0.37) | MMP1MMP3MMP7FPR2 | |
| SCHEMBL1666088 | 0.62 | CYP1A2 (0.34) | — | |
| Hydrochloric Acid SCHEMBL31149402 | 0.61 | ADRA2A (0.40) | MMP1MMP3MMP7FPR2 | |
| Hydrochloric Acid SCHEMBL28185499 | 0.60 | TAAR1 (0.39) | FPR2 | |
| SCHEMBL7109002 | 0.60 | HSPA5 (0.38) | — | |
| SCHEMBL31277140 | 0.59 | FPR2 (0.41) | MMP1MMP3MMP7FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7144887-B2 | Substituted 1,2,3-triazolo[1,5-a]quinazolines for enhancing cognition | MERCK SHARP & DOHME LTD. (GB) | 2006-12-05 | — | — | US | disclosed |
| US-20030125333-A1 | Substituted 1,2,3-triazolo[1,5-a]quinazolines for enhancing cognition | MERCK SHARP & DOHME LTD. (GB) | 2003-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030125333-A1 | Substituted 1,2,3-triazolo[1,5-a]quinazolines for enhancing cognition | HAX1, HTR1D, CHRM1 | MMP1 4328/4885MMP3 3907/4885MMP7 3762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.