SCHEMBL60686

SCHEMBL60686

O=C1CC(CCc2ccccc2)C(=O)O1

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FASN P49327 1/20 0.45
CYP3A4 P08684 1/20 0.42
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
SLC6A3 Q01959 1/20 0.39
TAAR1 Q96RJ0 1/20 0.38
KDM4E B2RXH2 1/20 0.38
MAPT P10636 1/20 0.38
HIF1A Q16665 1/20 0.38
PLA2G6 O60733 2/20 0.37
PLA2G4A P47712 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7352473 0.83 FASN (0.43) FASNSLC6A2SLC6A4SLC6A3
SCHEMBL13677474 0.83 FASN (0.43) FASNCYP3A4SLC6A2SLC6A4SLC6A3
SCHEMBL7431888 0.82 FASN (0.47) FASNCYP3A4SLC6A2SLC6A4SLC6A3
SCHEMBL7431881 0.82 FASN (0.47) FASNCYP3A4SLC6A2SLC6A4SLC6A3
SCHEMBL9740200 0.82 MAOB (0.45) FASNMAPT
SCHEMBL638641 0.82 MAOB (0.45) FASNMAPT
SCHEMBL10711852 0.82 FASN (0.47) FASNCYP3A4SLC6A2SLC6A4SLC6A3
SCHEMBL28863773 0.81 ALDH1A1 (0.40) FASNCYP3A4MAPT
SCHEMBL4168233 0.77 TSHR (0.44)
SCHEMBL14213794 0.76 CYP3A4 (0.34) FASNCYP3A4PLA2G6PLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10400099-B2 Halogen-free epoxy resin composition, prepreg, laminate and printed circuit board containing the same SHENGYI TECHNOLOGY CO., LTD. (CN) 2019-09-03 US disclosed
US-20170298218-A1 Halogen-Free Epoxy Resin Composition, Prepreg, Laminate and Printed Circuit Board Containing the Same SHENGYI TECHNOLOGY CO., LTD. (CN) 2017-10-19 US disclosed
US-8729195-B2 Organosilicon compound, method for producing thereof, and curable silicone composition containing the same DOW CORNING TORAY CO., LTD. (JP) 2014-05-20 US disclosed
US-20120309921-A1 Organosilicon Compound, Method For Producing Thereof, And Curable Silicone Composition Containing The Same DOW CORNING TORAY CO., LTD. (JP) 2012-12-06 US disclosed
US-20120309921-A1 Organosilicon Compound, Method For Producing Thereof, And Curable Silicone Composition Containing The Same DOW CORNING TORAY CO., LTD. (JP) 2012-12-06 US disclosed
US-8128959-B2 Polymeric pharmaceutical agent for treatment of cancer and method for production of the same HIROSHI MAEDA (JP) 2012-03-06 US disclosed
WO-2011081165-A1 ORGANOSILICON COMPOUND, METHOD FOR PRODUCING THEREOF, AND CURABLE SILICONE COMPOSITION CONTAINING THE SAME DOW CORNING TORAY CO., LTD. (JP) 2011-07-07 WO disclosed
US-7592311-B2 Platelet production promoting agent KYOWA HAKKO KIRIN CO., LTD. (JP) 2009-09-22 US disclosed
US-20090062476-A1 Polymeric pharmaceutical agent for treatment of cancer and method for production of the same MAEDA, HIROSHI (JP) 2009-03-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120309921-A1 Organosilicon Compound, Method For Producing Thereof, And Curable Silicone Composition Containing The Same SRM, ESD, THEM6 FASN 262/4885CYP3A4 3627/4885SLC6A2 4132/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.