Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 13/20 | 0.43 |
| ▸ | MAOA | P21397 | 9/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5819884 | 0.82 | MAOB (0.48) | MAOBMAOAHRH3PDK2NPC1 | |
| SCHEMBL6070482 | 0.73 | TUBB1 (0.42) | MAOBMAOANPC1ALDH1A1HPGD | |
| SCHEMBL3823883 | 0.69 | MAOB (0.62) | MAOBMAOARAB9ASMN1; SMN2ALOX5 | |
| SCHEMBL5801964 | 0.68 | MAOB (0.69) | MAOBMAOA | |
| SCHEMBL749857 | 0.68 | MEN1 (0.59) | MAOBMAOAHRH3NPC1RAB9A | |
| SCHEMBL6069668 | 0.68 | HRH3 (0.46) | MAOBMAOAHRH3PDK2ALOX5 | |
| SCHEMBL6069671 | 0.67 | MAOB (0.45) | MAOBMAOAHRH3PDK2NPC1 | |
| SCHEMBL31069846 | 0.66 | LMNA (0.67) | MAOBMAOARAB9ASMN1; SMN2ALOX5 | |
| SCHEMBL30628889 | 0.66 | MAOB (0.59) | MAOBMAOARAB9ASMN1; SMN2ALOX5 | |
| SCHEMBL281986 | 0.66 | LMNA (0.67) | MAOBMAOARAB9ASMN1; SMN2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006067416-A1 | CHEMICAL PROCESSES AND INTERMEDIATES | ASTRAZENECA AB (SE) | 2006-06-29 | — | — | WO | disclosed |