Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 6/20 | 0.39 |
| ▸ | ERN1 | O75460 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 4/20 | 0.36 |
| ▸ | MGAM | O43451 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | SI | P14410 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6069413 | 0.77 | MAOB (0.49) | TUBB1MAOBERN1MEN1KMT2A | |
| SCHEMBL5805630 | 0.74 | TUBB1 (0.45) | TUBB1MAOBERN1MEN1KMT2A | |
| SCHEMBL6069371 | 0.73 | MAOB (0.43) | MAOBALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL6070416 | 0.67 | TUBB4A (0.61) | TUBB1MAOBMEN1KMT2AALDH1A1 | |
| SCHEMBL435043 | 0.66 | ALDH1A1 (0.61) | TUBB1MAOBERN1ALDH1A1KDM4E | |
| SCHEMBL6035502 | 0.66 | TUBB1 (0.72) | TUBB1MAOBERN1MEN1KMT2A | |
| SCHEMBL24140500 | 0.65 | ERN1 (0.50) | TUBB1ERN1MEN1KMT2AALDH1A1 | |
| SCHEMBL20815159 | 0.65 | TUBB1 (0.58) | TUBB1MAOBERN1MEN1KMT2A | |
| SCHEMBL15175259 | 0.64 | ERN1 (0.56) | TUBB1MAOBERN1KDM4ENPC1 | |
| SCHEMBL7383233 | 0.64 | TUBB1 (0.55) | TUBB1MAOBERN1KDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006067416-A1 | CHEMICAL PROCESSES AND INTERMEDIATES | ASTRAZENECA AB (SE) | 2006-06-29 | — | — | WO | disclosed |