Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 8/20 | 0.37 |
| ▸ | MBTPS1 | Q14703 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 3/20 | 0.34 |
| ▸ | NOS1 | P29475 | 3/20 | 0.34 |
| ▸ | NOS2 | P35228 | 3/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6069793 | 0.94 | GHSR (0.39) | GHSRHDAC1NOS3NOS1NOS2 | |
| SCHEMBL6069733 | 0.90 | GHSR (0.35) | GHSRMBTPS1HDAC1NOS3NOS1 | |
| SCHEMBL6069728 | 0.85 | GHSR (0.40) | GHSRHDAC1NOS3NOS1NOS2 | |
| SCHEMBL6069720 | 0.81 | GHSR (0.36) | GHSRRIPK1TACR1 | |
| SCHEMBL7705076 | 0.81 | HDAC1 (0.35) | GHSRMBTPS1HDAC1SLC2A1RIPK1 | |
| SCHEMBL6069643 | 0.81 | GHSR (0.36) | GHSRMBTPS1HDAC1NOS3NOS1 | |
| SCHEMBL6069204 | 0.80 | NOS3 (0.56) | GHSRNOS3NOS1NOS2 | |
| SCHEMBL6069534 | 0.80 | RIPK1 (0.34) | GHSRRIPK1TACR1 | |
| SCHEMBL6069731 | 0.79 | GHSR (0.36) | GHSRNOS3NOS1NOS2RIPK1 | |
| SCHEMBL6070003 | 0.78 | TACR1 (0.34) | GHSRRIPK1TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067667-B2 | Aminoalkyl-3, 4-dihydroquinoline derivatives as no-synthase inhibitors | SCHERING AKTIENGESELLSCHAFT (DE) | 2006-06-27 | — | — | US | disclosed |
| US-20040127712-A1 | Aminoalkyl-3, 4-dihydroquinoline derivatives as no-synthase inhibitors | JAROCH STEFAN (DE) | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127712-A1 | Aminoalkyl-3, 4-dihydroquinoline derivatives as no-synthase inhibitors | NOS3, NOS1, NOS2 | GHSR 4522/4885MBTPS1 1027/4885HDAC1 1871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.