Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL181823 | 0.72 | — | — | |
| Chloroform SCHEMBL2457679 | 0.65 | ALDH1A1 (0.32) | ALDH1A1TSHR | |
| Chloroform SCHEMBL7066821 | 0.65 | ALDH1A1 (0.32) | ALDH1A1TSHR | |
| Chloroform SCHEMBL3805497 | 0.65 | ALDH1A1 (0.32) | ALDH1A1TSHR | |
| Chloroform SCHEMBL2455514 | 0.65 | ALDH1A1 (0.32) | ALDH1A1TSHR | |
| Chloroform SCHEMBL15163618 | 0.65 | ALDH1A1 (0.32) | ALDH1A1TSHR | |
| Chloroform SCHEMBL2454480 | 0.65 | ALDH1A1 (0.32) | ALDH1A1TSHR | |
| Chloroform SCHEMBL7067406 | 0.65 | ALDH1A1 (0.32) | ALDH1A1TSHR | |
| Chloroform SCHEMBL7067628 | 0.65 | ALDH1A1 (0.32) | ALDH1A1TSHR | |
| Chloroform SCHEMBL7070638 | 0.65 | ALDH1A1 (0.32) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067667-B2 | Aminoalkyl-3, 4-dihydroquinoline derivatives as no-synthase inhibitors | SCHERING AKTIENGESELLSCHAFT (DE) | 2006-06-27 | — | — | US | disclosed |
| US-20040127712-A1 | Aminoalkyl-3, 4-dihydroquinoline derivatives as no-synthase inhibitors | JAROCH STEFAN (DE) | 2004-07-01 | — | — | US | disclosed |
| EP-1115708-B1 | AMINOALKYL-3,4-DIHYDROQUINOLINE DERIVATES AS NO-SYNTHASE INHIBITORS | SCHERING AG (DE) | 2004-04-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127712-A1 | Aminoalkyl-3, 4-dihydroquinoline derivatives as no-synthase inhibitors | NOS3, NOS1, NOS2 | ALDH1A1 260/4885TSHR 4525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.