Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | IGF1R | P08069 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6070108 | 1.00 | DRD2 (0.51) | DRD2ADRA1AADRA1DADRA1BRECQL | |
| SCHEMBL7793671 | 0.90 | ADRA1D (0.62) | DRD2ADRA1AADRA1DADRA1BRECQL | |
| Hydrochloric Acid SCHEMBL7029018 | 0.89 | ADRA1D (0.61) | DRD2ADRA1AADRA1DADRA1BRECQL | |
| Hydrochloric Acid SCHEMBL7029024 | 0.89 | ADRA1D (0.61) | DRD2ADRA1AADRA1DADRA1BRECQL | |
| SCHEMBL6069916 | 0.88 | DRD2 (0.55) | DRD2ADRA1AADRA1DADRA1BRECQL | |
| SCHEMBL6070129 | 0.88 | DRD2 (0.55) | DRD2ADRA1AADRA1DADRA1BRECQL | |
| SCHEMBL7536579 | 0.87 | HTR1A (0.56) | DRD2ADRA1AADRA1DADRA1BRECQL | |
| SCHEMBL6070007 | 0.83 | MAPT (0.51) | DRD2ADRA1AADRA1DADRA1BRECQL | |
| SCHEMBL6069904 | 0.83 | MAPT (0.51) | DRD2ADRA1AADRA1DADRA1BRECQL | |
| SCHEMBL6181848 | 0.80 | MEN1 (0.55) | DRD2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067518-B2 | Pyridinyl-methyl-ethyl cyclohexanecarboxamides as serotonergic agents | WYETH (US) | 2006-06-27 | — | — | US | disclosed |
| US-20050107395-A1 | Pyridinyl-methyl-ethyl cyclohexanecarboxamides as serotonergic agents | WYETH | 2005-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107395-A1 | Pyridinyl-methyl-ethyl cyclohexanecarboxamides as serotonergic agents | HTR1A, HTR5A, HTR2C | DRD2 35/4885ADRA1A 47/4885ADRA1D 44/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.