Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6690927 | 0.85 | GRM2 (0.41) | SIGMAR1LMNABLM | |
| SCHEMBL18260436 | 0.80 | ACHE (0.45) | — | |
| SCHEMBL24209562 | 0.78 | ARG1 (0.49) | — | |
| SCHEMBL6071126 | 0.76 | GAA (0.40) | LMNABLM | |
| SCHEMBL7426458 | 0.72 | L3MBTL1 (0.40) | — | |
| SCHEMBL9422156 | 0.72 | SIGMAR1 (0.40) | SIGMAR1 | |
| SCHEMBL6716717 | 0.71 | EPHX2 (0.37) | LMNABLM | |
| SCHEMBL306308 | 0.71 | EPHX2 (0.37) | LMNABLM | |
| SCHEMBL6716719 | 0.71 | EPHX2 (0.37) | LMNABLM | |
| SCHEMBL10272560 | 0.71 | SIGMAR1 (0.35) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699909-B1 | MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS; CENTRAL NERVOUS SYSTEM DISORDERS | PRESCIENT NEUROPHARMA INC. (CA) | 2004-03-02 | — | — | US | disclosed |