Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 2/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28030092 | 0.94 | ADRB1 (0.58) | ADRB1ALOX5DRD2DRD3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5766987 | 0.93 | ADRB1 (0.56) | ADRB1ALOX5DRD2DRD3ALDH1A1 | |
| SCHEMBL7686995 | 0.74 | SIGMAR1 (0.56) | ALDH1A1POLBTSHRHSD17B10HTR1A | |
| SCHEMBL1825806 | 0.73 | ADRB1 (0.65) | ADRB1DRD2DRD3ALDH1A1L3MBTL1 | |
| SCHEMBL252862 | 0.73 | AR (0.41) | DRD2ALDH1A1L3MBTL1POLBMAPT | |
| SCHEMBL230424 | 0.72 | ADRB1 (1.00) | ADRB1DRD2DRD3ALDH1A1MAPT | |
| SCHEMBL5785574 | 0.72 | ADRB1 (1.00) | ADRB1DRD2DRD3ALDH1A1MAPT | |
| SCHEMBL11884832 | 0.72 | ALOX5 (0.48) | ADRB1ALOX5ALDH1A1L3MBTL1ALOX15 | |
| SCHEMBL29446047 | 0.72 | ADRB1 (1.00) | ADRB1DRD2DRD3ALDH1A1MAPT | |
| SCHEMBL10873929 | 0.72 | MGLL (0.37) | ADRB1ALOX5DRD2DRD3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060160794-A1 | Tachykinin receptor antagonists | ELI LILLY AND COMPANY | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160794-A1 | Tachykinin receptor antagonists | TACR1, TACR2, PROKR1 | ADRB1 112/4885ALOX5 1758/4885DRD2 1398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.