Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 2/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.46 |
| ▸ | DRD3 | P35462 | 6/20 | 0.43 |
| ▸ | HTR1A | P08908 | 5/20 | 0.43 |
| ▸ | HTR2A | P28223 | 5/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6071666 | 0.93 | BRAF (0.53) | BRAFSCN9ARAF1 | |
| SCHEMBL6072360 | 0.90 | SCN9A (0.51) | BRAFSCN9AMETRAF1 | |
| SCHEMBL6072492 | 0.88 | ADRB2 (0.47) | BCHEACHEMET | |
| SCHEMBL6072975 | 0.86 | RAF1 (0.54) | BRAFSCN9AMETRAF1 | |
| SCHEMBL6072145 | 0.85 | MET (0.47) | BRAFMETRAF1 | |
| SCHEMBL6072190 | 0.84 | HTT (0.46) | BRAFSCN9AMETRAF1 | |
| SCHEMBL6071686 | 0.84 | LMNA (0.48) | SCN9AMET | |
| SCHEMBL6072403 | 0.84 | FGFR1 (0.39) | BRAFMETRAF1 | |
| SCHEMBL6072240 | 0.83 | ALDH1A1 (0.49) | MET | |
| SCHEMBL6072249 | 0.83 | HRH3 (0.48) | BRAFMETRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060241149-A1 | Chemical compounds | ADAMS JERRY L | 2006-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241149-A1 | Chemical compounds | CHKB, MAP3K20, MAP3K6 | BRAF 191/4885SCN9A 4440/4885DRD3 4002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.