SCHEMBL607263

SCHEMBL607263

CC(C)(C)OC[C@@H](NC(=O)OCc1ccccc1)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CTSK P43235 8/20 0.61
CTSL P07711 3/20 0.61
CTSS P25774 3/20 0.61
PPARA Q07869 5/20 0.59
CTSB P07858 2/20 0.55
ITGB3 P05106 2/20 0.54
ITGA2B P08514 2/20 0.54
PPARG P37231 2/20 0.54
SYK P43405 1/20 0.53
ALDH1A1 P00352 1/20 0.51
ALOX15 P16050 1/20 0.51
KYNU Q16719 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1410812 1.00 CTSK (0.61) CTSKCTSLCTSSPPARACTSB
SCHEMBL1409909 1.00 CTSK (0.61) CTSKCTSLCTSSPPARACTSB
SCHEMBL3821264 0.95 CTSK (0.62) CTSKCTSLCTSSPPARACTSB
SCHEMBL31276612 0.95 CTSK (0.62) CTSKCTSLCTSSPPARACTSB
SCHEMBL3824387 0.91 CTSL (0.64) CTSKCTSLCTSSPPARACTSB
SCHEMBL1409906 0.91 CTSK (0.60) CTSKCTSLCTSSPPARACTSB
SCHEMBL29401640 0.91 CTSK (0.63) CTSKCTSLCTSSCTSBSYK
SCHEMBL344382 0.91 CTSK (0.63) CTSKCTSLCTSSCTSBSYK
SCHEMBL344381 0.91 CTSK (0.63) CTSKCTSLCTSSCTSBSYK
SCHEMBL30999365 0.90 CTSK (0.58) CTSKCTSLCTSSPPARACTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120041225-A1 KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF VAIDYA NITEEN A (US) 2012-02-16 US claimed
EP-1981831-A2 KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF Vaidya, Niteen A. (US) 2008-10-22 EP claimed
WO-2007092264-A2 KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF VAIDYA NITEEN A (US) 2007-08-16 WO claimed
US-20070185346-A1 Kit for automated resolving agent selection and method thereof VAIDYA NITEEN A 2007-08-09 US claimed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
CN-109928971-B Aryl substituted aminotetrahydropyrans and uses thereof 广东东阳光药业股份有限公司 2024-01-16 CN disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 US disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed
US-9242926-B2 Processes for the preparation of lacosamide and intermediates thereof CADILA HEALTHCARE LIMITED (IN) 2016-01-26 US disclosed
US-8940722-B2 Compounds for modulation of orphan nuclear receptor RAR-related orphan receptor-gamma (RORγ, NR1F3) activity and for the treatment of chronic inflammatory and autoimmune disease PHENEX PHARMACEUTICALS AG (DE) 2015-01-27 US disclosed
US-20070185346-A1 Kit for automated resolving agent selection and method thereof VAIDYA NITEEN A 2007-08-09 US disclosed
WO-2007050612-A1 2-AMINO-3,4-DIHYDRO-PYRIDO[3,4-D]PYRIMIDINE DERIVATIVES USEFUL AS INHIBITORS OF BETA-SECRETASE (BACE) JANSSEN PHARMACEUTICA N.V. (BE) 2007-05-03 WO disclosed
US-20050075281-A1 peptide antibiotics comprising lysobactin derivatives used for treatment and/or prophylaxis of bacterial infectious diseases; cyclic peptides BAYER HEALTHCARE AG (DE) 2005-04-07 US disclosed
US-20030092067-A1 Substrates and inhibitors of proteolytic enzymes PEPTIDE THERAPEUTICS LIMITED 2003-05-15 US disclosed
US-6528275-B1 Screening for cleavage using combinatorial fluorescence resonance energy transfer (FRET) compounds of given formula; can use to accelerate drug discovery process PEPTIDE THERAPEUTICS LIMITED (GB) 2003-03-04 US disclosed
EP-0906333-B1 SUBSTRATES AND INHIBITORS OF PROTEOLYTIC ENZYMES MEDIVIR UK LTD (GB) 2001-07-25 EP disclosed
EP-0906333-A2 SUBSTRATES AND INHIBITORS OF PROTEOLYTIC ENZYMES PEPTIDE THERAPEUTICS LIMITED (GB) 1999-04-07 EP disclosed
WO-1997040065-A2 SUBSTRATES AND INHIBITORS OF PROTEOLYTIC ENZYMES PEPTIDE THERAPEUTICS LIMITED (GB) 1997-10-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050075281-A1 peptide antibiotics comprising lysobactin derivatives used for treatment and/or prophylaxis of bacterial infectious diseases; cyclic peptides VIP, LNPEP, HAMP CTSK 393/4885CTSL 65/4885CTSS 459/4885
US-20120041225-A1 KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF ACKR3, KIT, C3AR1 CTSK 1088/4885CTSL 1121/4885CTSS 1371/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.