Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 17/20 | 0.52 |
| ▸ | PDE4A | P27815 | 17/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 15/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 15/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558524 | 0.79 | PDE4D (0.45) | PDE4DPDE4APDE4BPDE4CABCB11 | |
| SCHEMBL5794099 | 0.76 | PDE4D (0.65) | PDE4DPDE4APDE4BPDE4CABCB11 | |
| SCHEMBL4594035 | 0.76 | PDE4B (0.45) | PDE4DPDE4APDE4BPDE4CABCB11 | |
| SCHEMBL7654461 | 0.73 | PDE4B (0.40) | PDE4DPDE4APDE4BPDE4CABCB11 | |
| SCHEMBL16447382 | 0.70 | PARP10 (0.58) | PDE4DPDE4APDE4BPDE4CABCB11 | |
| SCHEMBL4544198 | 0.69 | PDE4B (0.71) | PDE4DPDE4APDE4BPDE4CABCB11 | |
| SCHEMBL1028814 | 0.69 | PDE4B (0.71) | PDE4DPDE4APDE4BPDE4CABCB11 | |
| SCHEMBL19205486 | 0.69 | PDE4B (0.64) | PDE4DPDE4APDE4BPDE4CABCB11 | |
| SCHEMBL5797196 | 0.69 | PDE4B (0.52) | PDE4DPDE4APDE4BPDE4CABCB11 | |
| SCHEMBL5797239 | 0.69 | PDE4D (0.49) | PDE4DPDE4APDE4BPDE4CABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006102069-A2 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF HYPERTENSION AND GASTROINTESTINAL DISORDERS | MICROBIA, INC. (US) | 2006-09-28 | — | — | WO | disclosed |