Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 17/20 | 0.40 |
| ▸ | PDE4A | P27815 | 14/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 14/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 14/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.35 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6073147 | 0.73 | PDE4D (0.52) | PDE4BPDE4APDE4CPDE4DABCB11 | |
| SCHEMBL4594035 | 0.73 | PDE4B (0.45) | PDE4BPDE4APDE4CPDE4DABCB11 | |
| SCHEMBL16447382 | 0.68 | PARP10 (0.58) | PDE4BPDE4APDE4CPDE4DABCB11 | |
| SCHEMBL5797239 | 0.67 | PDE4D (0.49) | PDE4BPDE4APDE4CPDE4DABCB11 | |
| SCHEMBL28334010 | 0.67 | PDE4B (0.48) | PDE4BPDE4APDE4CPDE4DABCB11 | |
| SCHEMBL15270511 | 0.65 | PDE4B (0.70) | PDE4BPDE4APDE4CPDE4DABCB11 | |
| SCHEMBL31015999 | 0.63 | PDE4B (0.44) | PDE4BPDE4APDE4CPDE4DABCB11 | |
| SCHEMBL5794099 | 0.62 | PDE4D (0.65) | PDE4BPDE4APDE4CPDE4DABCB11 | |
| SCHEMBL4402862 | 0.61 | PDE4B (0.46) | PDE4BPDE4APDE4CPDE4DABCB11 | |
| SCHEMBL2721695 | 0.61 | PARP10 (0.56) | PARP10PARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6498173-B1 | TREATMENT OF DISEASES BASED ON ACUTE OR CHRONIC OBSTRUCTION OF VESSELS AND/OR BRONCHI AND/OR INFLAMMATION | ALTANA PHARMA AG (DE) | 2002-12-24 | — | — | US | disclosed |