Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 2/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9068830 | 0.88 | MAPT (0.58) | MAPTALDH1A1SMN1; SMN2HSD17B10GSK3A | |
| SCHEMBL5275664 | 0.86 | MAPT (0.56) | MAPTALDH1A1SMN1; SMN2HSD17B10GSK3A | |
| SCHEMBL20176216 | 0.84 | MAPT (0.54) | MAPTALDH1A1SMN1; SMN2HSD17B10GSK3A | |
| SCHEMBL181852 | 0.82 | — | — | |
| SCHEMBL3138532 | 0.79 | GSK3A (0.56) | MAPTALDH1A1HSD17B10GSK3AGSK3B | |
| SCHEMBL11173506 | 0.78 | MAPT (0.56) | MAPTALDH1A1SMN1; SMN2HSD17B10GSK3A | |
| SCHEMBL1693423 | 0.78 | MAPT (0.56) | MAPTALDH1A1SMN1; SMN2HSD17B10GSK3A | |
| SCHEMBL1692808 | 0.78 | MAPT (0.56) | MAPTALDH1A1SMN1; SMN2HSD17B10GSK3A | |
| SCHEMBL2360918 | 0.78 | MAPT (0.56) | MAPTALDH1A1SMN1; SMN2HSD17B10GSK3A | |
| SCHEMBL2633830 | 0.78 | ALDH1A1 (0.58) | MAPTALDH1A1SMN1; SMN2HSD17B10GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2943584-B1 | MACROPHAGE IDENTIFICATION AGENT, AND IDENTIFICATION METHOD, SORTING METHOD, EVALUATION METHOD, SCREENING METHOD AND KIT USING THE MACROPHAGE IDENTIFIER AGENT | CANON KK (JP) | 2019-08-14 | — | — | EP | disclosed |
| US-10041937-B2 | Macrophage identification agent, and identification method, sorting method, evaluation method, screening method and kit using the macrophage identifier agent | CANON KABUSHIKI KAISHA (JP) | 2018-08-07 | — | — | US | disclosed |
| US-10041937-B2 | Macrophage identification agent, and identification method, sorting method, evaluation method, screening method and kit using the macrophage identifier agent | CANON KABUSHIKI KAISHA (JP) | 2018-08-07 | — | — | US | disclosed |
| US-20160018389-A1 | MACROPHAGE IDENTIFICATION AGENT, AND IDENTIFICATION METHOD, SORTING METHOD, EVALUATION METHOD, SCREENING METHOD AND KIT USING THE MACROPHAGE IDENTIFIER AGENT | CANON KABUSHIKI KAISHA (JP) | 2016-01-21 | — | — | US | disclosed |
| US-20160018389-A1 | MACROPHAGE IDENTIFICATION AGENT, AND IDENTIFICATION METHOD, SORTING METHOD, EVALUATION METHOD, SCREENING METHOD AND KIT USING THE MACROPHAGE IDENTIFIER AGENT | CANON KABUSHIKI KAISHA (JP) | 2016-01-21 | — | — | US | disclosed |
| US-9115122-B2 | Non-ATP dependent inhibitors of extracellular signal-regulated kinase (ERK) | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2015-08-25 | — | — | US | disclosed |
| WO-2014192972-A1 | MACROPHAGE IDENTIFICATION AGENT, AND IDENTIFICATION METHOD, SORTING METHOD, EVALUATION METHOD, SCREENING METHOD AND KIT USING THE MACROPHAGE IDENTIFIER AGENT | CANON KABUSHIKI KAISHA (JP) | 2014-12-04 | — | — | WO | disclosed |
| US-20140179743-A1 | NON-ATP DEPENDENT INHIBITORS OF EXTRACELLULAR SIGNAL-REGULATED KINASE (ERK) | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2014-06-26 | — | — | US | disclosed |
| US-20080090779-A1 | ANTIALLERGIC AGENTS | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2008-04-17 | — | — | US | disclosed |
| US-20070185059-A1 | Antiallergic agents | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2007-08-09 | — | — | US | disclosed |
| US-20070185110-A1 | Antiallergic agents | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2007-08-09 | — | — | US | disclosed |
| WO-2006013445-A2 | THIAZOLIDINEDIONE DERIVATIVES AS ALPHA ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080090779-A1 | ANTIALLERGIC AGENTS | NAT1, EPX, HRH2 | MAPT 2536/4885ALDH1A1 364/4885SMN1; SMN2 4693/4885 |
| US-10041937-B2 | Macrophage identification agent, and identification method, sorting method, evaluation method, screening method and kit using the macrophage identifier agent | CD68, MSR1, MYADM | MAPT 4796/4885ALDH1A1 582/4885SMN1; SMN2 4336/4885 |
| US-20140179743-A1 | NON-ATP DEPENDENT INHIBITORS OF EXTRACELLULAR SIGNAL-REGULATED KINASE (ERK) | MAPK1, MAP3K1, MAP3K20 | MAPT 3850/4885ALDH1A1 1499/4885SMN1; SMN2 4591/4885 |
| US-20070185110-A1 | Antiallergic agents | NAT1, EPX, AHR | MAPT 2469/4885ALDH1A1 340/4885SMN1; SMN2 4695/4885 |
| US-20070185059-A1 | Antiallergic agents | NAT1, EPX, AHR | MAPT 2415/4885ALDH1A1 362/4885SMN1; SMN2 4709/4885 |
| US-20160018389-A1 | MACROPHAGE IDENTIFICATION AGENT, AND IDENTIFICATION METHOD, SORTING METHOD, EVALUATION METHOD, SCREENING METHOD AND KIT USING THE MACROPHAGE IDENTIFIER AGENT | CD68, MSR1, MYADM | MAPT 4796/4885ALDH1A1 582/4885SMN1; SMN2 4336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.