SCHEMBL20176216

SCHEMBL20176216

CCCCCCCN1C(=O)CSC1=O

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.54
MGLL Q99685 5/20 0.48
PTGS1 P23219 3/20 0.48
PTGS2 P35354 3/20 0.48
FAAH O00519 3/20 0.48
ALDH1A1 P00352 2/20 0.45
GAA P10253 3/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.43
HSD17B10 Q99714 1/20 0.43
GSK3A P49840 1/20 0.42
GSK3B P49841 1/20 0.42
POLB P06746 1/20 0.41
TSHR P16473 1/20 0.40
CYP19A1 P11511 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5275664 0.98 MAPT (0.56) MAPTMGLLPTGS1PTGS2FAAH
SCHEMBL9068830 0.92 MAPT (0.58) MAPTALDH1A1GAAMEN1KMT2A
SCHEMBL6073396 0.84 MAPT (0.61) MAPTALDH1A1GAAMEN1KMT2A
SCHEMBL16274020 0.82 MEN1 (0.65) MAPTMGLLPTGS1PTGS2FAAH
SCHEMBL19220386 0.82 MEN1 (0.65) MAPTMGLLPTGS1PTGS2FAAH
SCHEMBL26286 0.82 MEN1 (0.65) MAPTMGLLPTGS1PTGS2FAAH
SCHEMBL14850663 0.82 MEN1 (0.65) MAPTMGLLPTGS1PTGS2FAAH
SCHEMBL20176213 0.82 MEN1 (0.65) MAPTMGLLPTGS1PTGS2FAAH
SCHEMBL28886326 0.82 MEN1 (0.65) MAPTMGLLPTGS1PTGS2FAAH
SCHEMBL6597634 0.81 MAPT (0.50) MAPTALDH1A1GAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180144877-A1 PHOTOELECTRIC CONVERSION ELEMENT, SOLAR CELL, AND COMPOUND FUJIFILM CORPORATION (JP) 2018-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180144877-A1 PHOTOELECTRIC CONVERSION ELEMENT, SOLAR CELL, AND COMPOUND SLC9A1, SLC9A2, SLC26A3 MAPT 1251/4885MGLL 3994/4885PTGS1 3885/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.