Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.42 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | SCN4A | P35499 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14519738 | 0.82 | LMNA (0.49) | HSD11B1GABBR2GABBR1MAPT | |
| SCHEMBL20747091 | 0.79 | RIPK1 (0.52) | HSD11B1MAPTSMN1; SMN2 | |
| SCHEMBL13543299 | 0.79 | RIPK1 (0.52) | HSD11B1MAPTSMN1; SMN2 | |
| SCHEMBL13543291 | 0.79 | RIPK1 (0.52) | HSD11B1MAPTSMN1; SMN2 | |
| SCHEMBL13844410 | 0.79 | KDM4E (0.46) | GABBR2GABBR1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL636737 | 0.79 | KDM4E (0.46) | GABBR2GABBR1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL4142251 | 0.79 | KDM4E (0.46) | GABBR2GABBR1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL288753 | 0.78 | GABBR2 (0.59) | GABBR2GABBR1KMT2ASMN1; SMN2SCN4A | |
| SCHEMBL59840 | 0.78 | GABBR2 (0.59) | GABBR2GABBR1KMT2ASMN1; SMN2SCN4A | |
| SCHEMBL123765 | 0.78 | GABBR2 (0.59) | GABBR2GABBR1KMT2ASMN1; SMN2SCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006069798-A1 | PROCESS FOR THE PREPARATION OF CHIRAL AMINES | DSM IP ASSETS B.V. (NL) | 2006-07-06 | — | — | WO | disclosed |