Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8673567 | 0.82 | HTT (0.44) | HTTHPGDALOX5HSD17B10KDM4E | |
| SCHEMBL6077824 | 0.78 | ALOX5 (0.36) | HTTHPGDNPC1MAPK1RAB9A | |
| SCHEMBL1979635 | 0.78 | CYP4F2 (0.51) | HTTHPGDHSD17B10KDM4EMAPT | |
| SCHEMBL292988 | 0.77 | PTGS2 (0.43) | HTTALOX5HSD17B10KDM4EMAPT | |
| SCHEMBL3156904 | 0.77 | KDM4E (0.52) | HTTHPGDHSD17B10KDM4EMAPT | |
| SCHEMBL24202214 | 0.77 | HTT (0.45) | HTTHPGDHSD17B10KDM4EMAPT | |
| SCHEMBL1974691 | 0.77 | HTT (0.45) | HTTHPGDALOX5HSD17B10KDM4E | |
| SCHEMBL15463134 | 0.76 | HTT (0.41) | HTTHPGDRAB9AALOX5HSD17B10 | |
| SCHEMBL27930395 | 0.76 | TRPV1 (0.46) | HTTHPGDNPC1MAPK1RAB9A | |
| SCHEMBL28717635 | 0.75 | THRB (0.45) | HTTHPGDHSD17B10KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103980109-B | Process for preparing (2, 4-dimethylbiphenyl-3-yl) acetic acid, esters thereof and intermediate compounds | 拜尔农作物科学股份公司 | 2017-05-03 | — | — | CN | disclosed |
| CN-103980109-A | Process for preparing (2, 4-dimethylbiphenyl-3-yl) acetic acid, esters thereof and intermediate compounds | BAYER CROPSCIENCE AG | 2014-08-13 | — | — | CN | disclosed |
| CN-102471215-B | Process for preparing (2, 4-dimethylbiphenyl-3-yl) acetic acid, esters thereof and intermediate compounds | BAYER CROPSCIENCE AG | 2014-06-11 | — | — | CN | disclosed |
| CN-102471215-A | Process for preparing (2, 4-dimethylbiphenyl-3-yl) acetic acid, esters thereof and intermediate compounds | BAYER CROPSCIENCE AG | 2012-05-23 | — | — | CN | disclosed |
| EP-2451767-A2 | METHOD FOR PRODUCING (2,4-DIMETHYLBIPHENYL-3-YL)ACETIC ACIDS, THE ESTERS THEREOF AND INTERMEDIATE COMPOUNDS | Bayer CropScience AG (DE) | 2012-05-16 | — | — | EP | disclosed |
| WO-2011003530-A8 | METHOD FOR PRODUCING (2,4-DIMETHYLBIPHENYL-3-YL)ACETIC ACIDS, THE ESTERS THEREOF AND INTERMEDIATE COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2012-01-12 | — | — | WO | disclosed |
| WO-2011003530-A3 | METHOD FOR PRODUCING (2,4-DIMETHYLBIPHENYL-3-YL)ACETIC ACIDS, THE ESTERS THEREOF AND INTERMEDIATE COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2011-03-17 | — | — | WO | disclosed |
| WO-2011003530-A2 | METHOD FOR PRODUCING (2,4-DIMETHYLBIPHENYL-3-YL)ACETIC ACIDS, THE ESTERS THEREOF AND INTERMEDIATE COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2011-01-13 | — | — | WO | disclosed |