Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ATP4A | P20648 | 3/20 | 0.35 |
| ▸ | ATP4B | P51164 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6076329 | 0.78 | SMN1; SMN2 (0.40) | TSHRATP4AATP4BHTTSTAT3 | |
| SCHEMBL6077441 | 0.72 | TDP1 (0.36) | TSHRATP4AATP4BHTTSTAT3 | |
| SCHEMBL6077445 | 0.70 | THRA (0.42) | TSHRHTTSTAT3SMN1; SMN2L3MBTL1 | |
| SCHEMBL6078583 | 0.69 | SMN1; SMN2 (0.35) | TSHRATP4AATP4BHTTSTAT3 | |
| SCHEMBL6078590 | 0.68 | L3MBTL1 (0.38) | TSHRHTTSTAT3SMN1; SMN2L3MBTL1 | |
| SCHEMBL3103639 | 0.67 | L3MBTL1 (0.50) | TSHRHTTSTAT3SMN1; SMN2L3MBTL1 | |
| SCHEMBL24646118 | 0.67 | CYP4F2 (0.56) | L3MBTL1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL28969202 | 0.67 | CYP4F2 (0.56) | L3MBTL1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL24645960 | 0.67 | CYP4F2 (0.56) | L3MBTL1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL15459483 | 0.65 | TSHR (0.47) | TSHRATP4AATP4BHTTSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067668-B2 | 4-quinolinol derivatives and fungicides containing the same as an active ingredient used for agriculture and horticulture | MEIJI SEIKA KAISHA, LTD. (JP) | 2006-06-27 | — | — | US | disclosed |
| EP-0990648-B1 | 4-QUINOLINOL DERIVATIVES AND AGROHORTICULTURAL BACTERICIDES CONTAINING THE SAME AS ACTIVE INGREDIENT | MEIJI SEIKA KAISHA (JP) | 2005-11-02 | — | — | EP | disclosed |
| US-20040152728-A1 | 4-Quinolinol derivatives and fungicides containing the same as an active ingredient used for agriculture and horticulture | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-08-05 | — | — | US | disclosed |
| US-6680282-B2 | FUNGICIDE HAVING AN EXCELLENT CONTROL EFFECT; 4-QUINOLINOL DERIVATIVES HAVING SPECIFIC SUBSTITUENT AT 1,2 AND ATLEAST ONE SUBSTITUENT AT 5,6,7,8 POSITION | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-01-20 | — | — | US | disclosed |
| US-20030119863-A1 | 4-Quinolinol derivatives and agrohorticultural bactericides containing the same as active ingredient | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2003-06-26 | — | — | US | disclosed |
| EP-0990648-A1 | 4-QUINOLINOL DERIVATIVES AND AGROHORTICULTURAL BACTERICIDES CONTAINING THE SAME AS ACTIVE INGREDIENT | Meiji Seika Kaisha, Ltd. (JP) | 2000-04-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152728-A1 | 4-Quinolinol derivatives and fungicides containing the same as an active ingredient used for agriculture and horticulture | CYP51A1, CYP4X1, CYP4Z1 | TSHR 4067/4885ATP4A 534/4885ATP4B 444/4885 |
| US-20030119863-A1 | 4-Quinolinol derivatives and agrohorticultural bactericides containing the same as active ingredient | CYP51A1, DDT, PGLS | TSHR 4551/4885ATP4A 1843/4885ATP4B 1058/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.