Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ATP4A | P20648 | 2/20 | 0.40 |
| ▸ | ATP4B | P51164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16651446 | 0.81 | GAA (0.38) | SMN1; SMN2STAT3HTTL3MBTL1MAPT | |
| SCHEMBL6077263 | 0.78 | TSHR (0.36) | SMN1; SMN2STAT3HTTATP4AATP4B | |
| SCHEMBL16652098 | 0.77 | RORC (0.47) | SMN1; SMN2ATP4AATP4BL3MBTL1MAPT | |
| SCHEMBL348875 | 0.77 | MEN1 (0.55) | SMN1; SMN2L3MBTL1MAPTGAAHPGD | |
| SCHEMBL6077445 | 0.76 | THRA (0.42) | SMN1; SMN2STAT3HTTL3MBTL1MAPT | |
| SCHEMBL6077441 | 0.76 | TDP1 (0.36) | SMN1; SMN2STAT3HTTATP4AATP4B | |
| SCHEMBL26608216 | 0.75 | L3MBTL1 (0.47) | SMN1; SMN2STAT3HTTATP4AATP4B | |
| SCHEMBL3103639 | 0.73 | L3MBTL1 (0.50) | SMN1; SMN2STAT3HTTL3MBTL1MAPT | |
| SCHEMBL3092046 | 0.72 | MAPT (0.42) | SMN1; SMN2STAT3HTTMAPTGAA | |
| SCHEMBL13096638 | 0.72 | HTT (0.42) | SMN1; SMN2STAT3HTTL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067668-B2 | 4-quinolinol derivatives and fungicides containing the same as an active ingredient used for agriculture and horticulture | MEIJI SEIKA KAISHA, LTD. (JP) | 2006-06-27 | — | — | US | disclosed |
| EP-0990648-B1 | 4-QUINOLINOL DERIVATIVES AND AGROHORTICULTURAL BACTERICIDES CONTAINING THE SAME AS ACTIVE INGREDIENT | MEIJI SEIKA KAISHA (JP) | 2005-11-02 | — | — | EP | disclosed |
| US-20040152728-A1 | 4-Quinolinol derivatives and fungicides containing the same as an active ingredient used for agriculture and horticulture | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-08-05 | — | — | US | disclosed |
| US-6680282-B2 | FUNGICIDE HAVING AN EXCELLENT CONTROL EFFECT; 4-QUINOLINOL DERIVATIVES HAVING SPECIFIC SUBSTITUENT AT 1,2 AND ATLEAST ONE SUBSTITUENT AT 5,6,7,8 POSITION | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-01-20 | — | — | US | disclosed |
| US-20030119863-A1 | 4-Quinolinol derivatives and agrohorticultural bactericides containing the same as active ingredient | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2003-06-26 | — | — | US | disclosed |
| EP-0990648-A1 | 4-QUINOLINOL DERIVATIVES AND AGROHORTICULTURAL BACTERICIDES CONTAINING THE SAME AS ACTIVE INGREDIENT | Meiji Seika Kaisha, Ltd. (JP) | 2000-04-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152728-A1 | 4-Quinolinol derivatives and fungicides containing the same as an active ingredient used for agriculture and horticulture | CYP51A1, CYP4X1, CYP4Z1 | SMN1; SMN2 4492/4885STAT3 3195/4885HTT 1245/4885 |
| US-20030119863-A1 | 4-Quinolinol derivatives and agrohorticultural bactericides containing the same as active ingredient | CYP51A1, DDT, PGLS | SMN1; SMN2 4579/4885STAT3 2947/4885HTT 947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.