SCHEMBL607731

SCHEMBL607731

NNC(=O)Nc1ccc(C(=O)O)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 4/20 0.58
NR1H4 Q96RI1 1/20 0.58
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
ALDH1A1 P00352 1/20 0.53
MITF O75030 1/20 0.52
CA2 P00918 2/20 0.51
CA12 O43570 1/20 0.51
CA9 Q16790 1/20 0.51
FFAR1 O14842 1/20 0.50
NAMPT P43490 1/20 0.50
POLB P06746 1/20 0.50
TP53 P04637 1/20 0.50
TSHR P16473 1/20 0.50
FAAH O00519 1/20 0.49
CA1 P00915 1/20 0.49
HPSE Q9Y251 1/20 0.49
PTPN11 Q06124 1/20 0.49
NPC1 O15118 1/20 0.48
MAPT P10636 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4745756 0.87 EPHX2 (0.71) EPHX2NR1H4MEN1KMT2AALDH1A1
Urea SCHEMBL4746502 0.85 EPHX2 (0.65) EPHX2NR1H4MEN1KMT2AALDH1A1
Terephthalic Acid SCHEMBL998372 0.84 TSHR (0.63) ALDH1A1CA2CA12CA9TP53
SCHEMBL7883674 0.82 MAPT (0.76) EPHX2NR1H4MEN1KMT2AALDH1A1
SCHEMBL1019968 0.81 EPHX2 (0.74) EPHX2NR1H4MEN1KMT2AALDH1A1
SCHEMBL28513066 0.81 EPHX2 (0.59) EPHX2NR1H4MEN1KMT2AALDH1A1
SCHEMBL712280 0.80 SMN1; SMN2 (0.73) EPHX2MEN1KMT2AALDH1A1CA2
SCHEMBL456985 0.80 ALDH1A1 (0.70) MEN1KMT2AALDH1A1CA2CA9
SCHEMBL2834402 0.80 MITF (0.68) MEN1KMT2AALDH1A1MITFCA2
SCHEMBL3885202 0.79 EPHX2 (0.62) EPHX2NR1H4MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250243161-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2025-07-31 US disclosed
US-12269800-B2 Delivery of therapeutic alkaloid compounds SENSORIUM THERAPEUTICS, INC. (US) 2025-04-08 US disclosed
US-20250051277-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2025-02-13 US disclosed
US-20240246910-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2024-07-25 US disclosed
US-11999694-B2 Delivery of therapeutic alkaloid compounds SENSORIUM THERAPEUTICS, INC. (US) 2024-06-04 US disclosed
US-20230159455-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2023-05-25 US disclosed
US-20230159455-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2023-05-25 US disclosed
US-20230159455-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2023-05-25 US disclosed
WO-2023076586-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. (US) 2023-05-04 WO disclosed
WO-2023076586-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. (US) 2023-05-04 WO disclosed
US-4518533-A Azetidinone-4-disulfides as intermediates for thia-aza compounds with a beta-lactam ring CIBA GEIGY CORPORATION (US) 1985-05-21 US disclosed
US-4515717-A INTERMEDIATES FOR 6-UNSUBSTITUTED PENICILLIN ANTIOBIOTICS CIBA GEIGY CORPORATION (US) 1985-05-07 US disclosed
US-4500457-A TREATING AN ACYLOXYAZETIDINONE WITH MERCAPTO COMPOUND, GLYOYLIC ESTER, HALOGENATION AGENT, AND PHOSPHINE COMPOUNT THEN CYCLIZATION CIBA-GEIGY CORPORATION (US) 1985-02-19 US disclosed
US-4447360-A Intermediates for thia-aza compounds with a β-lactam ring CIBA-GEIGY CORPORATION (US) 1984-05-08 US disclosed
EP-0003960-B1 6-SUBSTITUTED THIA-AZA-COMPOUNDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM CIBA-GEIGY AG (CH) 1983-06-29 EP disclosed
US-4331676-A 2-PENEM COMPOUNDS UNSUBSTITUTED IN THE 6 POSITION CIBA-GEIGY CORPORATION (US) 1982-05-25 US disclosed
EP-0042026-A1 3,4-Disubstituted azetidin-2-on compounds and process for their preparation CIBA-GEIGY AG (CH) 1981-12-23 EP disclosed
EP-0003960-A1 6-Substituted thia-aza-compounds, their preparation and pharmaceutical compositions containing them CIBA-GEIGY AG (CH) 1979-09-19 EP disclosed
US-3950362-A OXABICYCLOOCTANES AND PROCESS FOR THEIR MANUFACTURE CIBA-GEIGY CORPORATION (US) 1976-04-13 US disclosed
US-3941813-A Dioxatricyclodecanes and process for their manufacture CIBA-GEIGY CORPORATION (US) 1976-03-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250051277-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS PNMT, HNMT, NNMT EPHX2 1841/4885NR1H4 703/4885MEN1 163/4885
US-20250243161-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS PNMT, HNMT, NNMT EPHX2 1841/4885NR1H4 703/4885MEN1 163/4885
US-20230159455-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS PNMT, HNMT, NNMT EPHX2 1841/4885NR1H4 703/4885MEN1 163/4885
US-20240246910-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS PNMT, HNMT, NNMT EPHX2 1841/4885NR1H4 703/4885MEN1 163/4885
US-12269800-B2 Delivery of therapeutic alkaloid compounds PNMT, HNMT, NNMT EPHX2 1841/4885NR1H4 703/4885MEN1 163/4885
US-11999694-B2 Delivery of therapeutic alkaloid compounds PNMT, HNMT, NNMT EPHX2 1841/4885NR1H4 703/4885MEN1 163/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.