Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6076907 | 0.78 | CYP2C9 (0.41) | — | |
| SCHEMBL6078396 | 0.78 | HDAC4 (0.40) | LMNAHDAC4HDAC1 | |
| SCHEMBL6077888 | 0.76 | MMP1 (0.35) | — | |
| SCHEMBL6077657 | 0.74 | GAA (0.45) | LMNAGAA | |
| SCHEMBL6078844 | 0.73 | ALDH1A1 (0.46) | POLBGAA | |
| SCHEMBL6078979 | 0.69 | — | — | |
| SCHEMBL6079130 | 0.67 | — | — | |
| SCHEMBL6078230 | 0.66 | — | — | |
| SCHEMBL6078345 | 0.64 | HDAC6 (0.35) | — | |
| SCHEMBL14612064 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7022317-B2 | Heterocyclic derivatives of 2-oxothiazolidine-4-carboxylic acid, and use as active photoprotective agents | L'OREAL (FR) | 2006-04-04 | — | — | US | claimed |
| US-20050129635-A1 | Novel heterocyclic derivatives of 2-oxothiazolidine-4-carboxylic acid, and use as active photoprotective agents | L'OREAL S.A. (FR) | 2005-06-16 | — | — | US | claimed |
| US-7022317-B2 | Heterocyclic derivatives of 2-oxothiazolidine-4-carboxylic acid, and use as active photoprotective agents | L'OREAL (FR) | 2006-04-04 | — | — | US | disclosed |
| US-20050129635-A1 | Novel heterocyclic derivatives of 2-oxothiazolidine-4-carboxylic acid, and use as active photoprotective agents | L'OREAL S.A. (FR) | 2005-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050129635-A1 | Novel heterocyclic derivatives of 2-oxothiazolidine-4-carboxylic acid, and use as active photoprotective agents | CUTA, OGDH, TYR | LMNA 3284/4885POLB 1014/4885GAA 1184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.