Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.35 |
| ▸ | CCR5 | P51681 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | VDR | P11473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6076907 | 0.83 | CYP2C9 (0.41) | CYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL6077888 | 0.81 | MMP1 (0.35) | — | |
| SCHEMBL6077284 | 0.77 | KMT2A (0.40) | GAAHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL6078396 | 0.77 | HDAC4 (0.40) | LMNACYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL6078345 | 0.76 | HDAC6 (0.35) | — | |
| SCHEMBL6078844 | 0.75 | ALDH1A1 (0.46) | GAACYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL6077929 | 0.74 | LMNA (0.37) | GAALMNA | |
| SCHEMBL6078148 | 0.74 | NPSR1 (0.43) | GAALMNAMEN1KMT2AABCG2 | |
| SCHEMBL10558628 | 0.73 | GAA (0.39) | GAALMNACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6077282 | 0.72 | HDAC4 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7022317-B2 | Heterocyclic derivatives of 2-oxothiazolidine-4-carboxylic acid, and use as active photoprotective agents | L'OREAL (FR) | 2006-04-04 | — | — | US | claimed |
| US-20050129635-A1 | Novel heterocyclic derivatives of 2-oxothiazolidine-4-carboxylic acid, and use as active photoprotective agents | L'OREAL S.A. (FR) | 2005-06-16 | — | — | US | claimed |
| EP-1471067-A1 | Derivatives of 2-oxothiadiazoline-4-carboxylic acid and its use as active photoprotective agent | L'OREAL (FR) | 2004-10-27 | — | — | EP | claimed |
| US-7022317-B2 | Heterocyclic derivatives of 2-oxothiazolidine-4-carboxylic acid, and use as active photoprotective agents | L'OREAL (FR) | 2006-04-04 | — | — | US | disclosed |
| US-20050129635-A1 | Novel heterocyclic derivatives of 2-oxothiazolidine-4-carboxylic acid, and use as active photoprotective agents | L'OREAL S.A. (FR) | 2005-06-16 | — | — | US | disclosed |
| EP-1471067-A1 | Derivatives of 2-oxothiadiazoline-4-carboxylic acid and its use as active photoprotective agent | L'OREAL (FR) | 2004-10-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050129635-A1 | Novel heterocyclic derivatives of 2-oxothiazolidine-4-carboxylic acid, and use as active photoprotective agents | CUTA, OGDH, TYR | GAA 1184/4885LMNA 3284/4885CYP3A4 443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.