Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.53 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | HPGDS | O60760 | 1/20 | 0.51 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.51 |
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.51 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.51 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.48 |
| ▸ | OGG1 | O15527 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL607806 | 1.00 | CA2 (0.53) | CA2CA1CA12CA9HPGDS | |
| SCHEMBL9716715 | 0.87 | ERAP2 (0.55) | CA2CA1CA12CA9HPGDS | |
| SCHEMBL7034236 | 0.87 | LNPEP (0.60) | CA2CA1CA12CA9HPGDS | |
| SCHEMBL7034241 | 0.87 | LNPEP (0.60) | CA2CA1CA12CA9HPGDS | |
| SCHEMBL9716710 | 0.87 | ERAP2 (0.55) | CA2CA1CA12CA9HPGDS | |
| SCHEMBL607886 | 0.87 | ITGB3 (0.60) | CA2CA1CA12CA9HPGDS | |
| SCHEMBL607885 | 0.87 | ITGB3 (0.60) | CA2CA1CA12CA9HPGDS | |
| SCHEMBL24518200 | 0.86 | CA2 (0.55) | CA2CA1CA12CA9HPGDS | |
| SCHEMBL1767664 | 0.86 | CA2 (0.55) | CA2CA1CA12CA9HPGDS | |
| SCHEMBL17104377 | 0.86 | HPGDS (0.54) | CA2CA1CA12CA9HPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040915-A1 | PEPTIDES AND NANOPARTICLES FOR THERAPEUTIC AND DIAGNOSTIC APPLICATIONS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-02-16 | — | — | US | claimed |
| WO-2010088527-A2 | PEPTIDES AND NANOPARTICLES FOR THERAPEUTIC AND DIAGNOSTIC APPLICATIONS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2010-08-05 | — | — | WO | claimed |
| US-9163063-B2 | Peptides and nanoparticles for therapeutic and diagnostic applications | TRUSTEES OF DARMOUTH COLLEGE (US) | 2015-10-20 | — | — | US | disclosed |
| US-20140329760-A1 | PEPTIDES AND NANOPARTICLES FOR THERAPEUTIC AND DIAGNOSTIC APPLICATIONS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2014-11-06 | — | — | US | disclosed |
| US-8658601-B2 | Peptides and nanoparticles for therapeutic and diagnostic applications | TRUSTEES OF DARTMOUTH COLLEGE (US) | 2014-02-25 | — | — | US | disclosed |
| US-20120040915-A1 | PEPTIDES AND NANOPARTICLES FOR THERAPEUTIC AND DIAGNOSTIC APPLICATIONS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-02-16 | — | — | US | disclosed |
| WO-2010088527-A2 | PEPTIDES AND NANOPARTICLES FOR THERAPEUTIC AND DIAGNOSTIC APPLICATIONS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2010-08-05 | — | — | WO | disclosed |