Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 6/20 | 0.46 |
| ▸ | BRAF | P15056 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 6/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3103022 | 0.89 | KMT2A (0.46) | RAF1BRAFLMNAPOLBHTT | |
| SCHEMBL3108474 | 0.89 | RAF1 (0.46) | RAF1BRAFLMNAPOLBHTT | |
| SCHEMBL425521 | 0.88 | RAF1 (0.51) | RAF1BRAFLMNAKDM4EALDH1A1 | |
| SCHEMBL3109324 | 0.86 | ALDH1A1 (0.47) | RAF1BRAFLMNAPOLBMTOR | |
| SCHEMBL3113688 | 0.86 | MAPT (0.48) | RAF1BRAFLMNAPOLBHSD17B10 | |
| SCHEMBL427735 | 0.85 | RAB9A (0.46) | RAF1BRAFLMNAPOLBKDM4E | |
| SCHEMBL3121338 | 0.85 | ALDH1A1 (0.43) | RAF1BRAFPOLBKDM4EALDH1A1 | |
| SCHEMBL11926322 | 0.84 | RAF1 (0.47) | RAF1BRAFHSD17B10KDM4EALDH1A1 | |
| SCHEMBL3114692 | 0.84 | RAF1 (0.50) | RAF1BRAFLMNAKDM4E | |
| SCHEMBL3114282 | 0.84 | THRB (0.45) | RAF1BRAFLMNAPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060223996-A1 | IL-12 modulatory compounds | SYNTA PHARMACEUTICALS CORP. (US) | 2006-10-05 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060223996-A1 | IL-12 modulatory compounds | IL2, IL4, IFNG | RAF1 2782/4885BRAF 2713/4885LMNA 4101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.