Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 9/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 9/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 9/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 7/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6079661 | 1.00 | CHRM2 (0.48) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL6079656 | 1.00 | CHRM2 (0.48) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL3608442 | 0.78 | MEN1 (0.43) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL8570755 | 0.74 | CHRM2 (0.66) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL4305542 | 0.73 | LTA4H (0.48) | MEN1KMT2ALTA4HSIGMAR1 | |
| SCHEMBL42501 | 0.71 | ACHE (0.58) | LTA4HCYP2D6DRD2DRD3SIGMAR1 | |
| SCHEMBL330609 | 0.71 | ACHE (0.58) | LTA4HCYP2D6DRD2DRD3SIGMAR1 | |
| SCHEMBL239922 | 0.71 | ACHE (0.58) | LTA4HCYP2D6DRD2DRD3SIGMAR1 | |
| SCHEMBL14793661 | 0.71 | ACHE (0.58) | LTA4HCYP2D6DRD2DRD3SIGMAR1 | |
| SCHEMBL25090864 | 0.71 | HRH2 (0.35) | LTA4HHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060094716-A1 | 1-Pyridin-4-yl-urea derivatives | ACTELION PHARMACEUTICALS LTD (CH) | 2006-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094716-A1 | 1-Pyridin-4-yl-urea derivatives | P2RY4, P2RX4, REN | CHRM2 63/4885CHRM1 34/4885CHRM3 83/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.