Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.49 |
| ▸ | MELK | Q14680 | 1/20 | 0.49 |
| ▸ | STK24 | Q9Y6E0 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.36 |
| ▸ | BCHE | P06276 | 3/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.35 |
| ▸ | GRK6 | P43250 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11926107 | 0.80 | PTPN1 (0.41) | JAK2RPS6KA3CHEK1PTPN1ROCK1 | |
| SCHEMBL5745026 | 0.78 | PTPN1 (0.35) | JAK2RPS6KA3CHEK1PTPN1ROCK1 | |
| SCHEMBL5745495 | 0.74 | DHODH (0.39) | JAK2RPS6KA3CHEK1PTPN1ROCK1 | |
| SCHEMBL8974681 | 0.74 | KDM4E (0.39) | JAK2RPS6KA3CHEK1PTPN1ROCK1 | |
| SCHEMBL3021978 | 0.73 | CYP2A6 (0.39) | JAK2RPS6KA3CHEK1PTPN1ROCK1 | |
| SCHEMBL27311719 | 0.72 | ALDH1A1 (0.44) | PTPN1KDM4EGAAHPGDMEN1 | |
| SCHEMBL22914881 | 0.72 | ADRB2 (0.48) | KDM4EGAAHPGDMEN1KMT2A | |
| SCHEMBL24367974 | 0.70 | JAK2 (0.58) | JAK2RPS6KA3MELKSTK24PARP1 | |
| SCHEMBL8974440 | 0.70 | KCNN2 (0.40) | PTPN1RECQLHPGDMEN1KMT2A | |
| SCHEMBL168637 | 0.70 | JAK2 (0.61) | JAK2RPS6KA3MELKSTK24PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060041123-A1 | Antibacterial agents | GLAXO GROUP LIMITED (GB) | 2006-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060041123-A1 | Antibacterial agents | NQO2, NRDC, IFNG | JAK2 4227/4885RPS6KA3 765/4885MELK 1838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.