Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 3/20 | 0.45 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6080359 | 0.90 | BACE1 (0.47) | — | |
| SCHEMBL6593434 | 0.82 | ALDH1A1 (0.49) | HRH4ALDH1A1GAATSHRTMEM97 | |
| SCHEMBL6080164 | 0.80 | HRH4 (0.46) | HRH4MAPK1HTR6AVPR2AVPR1A | |
| SCHEMBL6079907 | 0.79 | PTGER1 (0.43) | ALDH1A1TSHRMEN1MAPK1KMT2A | |
| SCHEMBL6080313 | 0.79 | TSHR (0.41) | ALDH1A1TSHRMAPK1HSD17B10 | |
| SCHEMBL6080492 | 0.78 | HRH3 (0.39) | ALDH1A1GAATSHRMEN1KMT2A | |
| SCHEMBL6080327 | 0.78 | SIRT6 (0.44) | TMEM97SIGMAR1MAPK1KMT2AHTR6 | |
| SCHEMBL6080654 | 0.77 | LTB4R (0.41) | ALDH1A1TSHRMAPK1HSD17B10 | |
| SCHEMBL6080127 | 0.75 | ALDH1A1 (0.49) | HRH4ALDH1A1GAATSHRTMEM97 | |
| SCHEMBL6594367 | 0.75 | HRH4 (0.47) | HRH4ALDH1A1GAATSHRTMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NEURO3D (FR) | 2006-08-17 | — | — | US | claimed |
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NEURO3D (FR) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NQO1, NQO2, RECQL | HRH4 619/4885ALDH1A1 2726/4885GAA 589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.