Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 1/20 | 0.60 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6077882 | 0.84 | ALDH1A1 (0.77) | MEN1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL6078456 | 0.82 | IDH1 (0.50) | CA2 | |
| SCHEMBL29398619 | 0.82 | IDH1 (0.50) | CA2 | |
| SCHEMBL6079248 | 0.82 | MEN1 (0.58) | MEN1ALDH1A1KMT2A | |
| SCHEMBL6078655 | 0.81 | ALOX12 (0.45) | CA2 | |
| SCHEMBL6078851 | 0.81 | ALDH1A1 (0.62) | MEN1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL6079548 | 0.81 | ALDH1A1 (0.59) | MEN1ALDH1A1KMT2A | |
| SCHEMBL6427772 | 0.81 | IDH1 (0.48) | — | |
| SCHEMBL6080277 | 0.81 | PKM (0.61) | HSD17B2MEN1ALDH1A1KMT2ACA2 | |
| SCHEMBL6078277 | 0.80 | LMNA (0.67) | MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7071231-B2 | Naphthalene ureas as glucose uptake enhancers | TELIK, INC. (US) | 2006-07-04 | — | — | US | disclosed |
| US-6458998-B1 | NAPHTHALENEUREAS AS ANTIDIABETIC AGENTS | TELIK, INC. | 2002-10-01 | — | — | US | disclosed |