Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ASPH | Q12797 | 1/20 | 0.40 |
| ▸ | IGFBP3 | P17936 | 3/20 | 0.39 |
| ▸ | KMO | O15229 | 5/20 | 0.37 |
| ▸ | RBP4 | P02753 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | IGFBP1 | P08833 | 1/20 | 0.34 |
| ▸ | IGFBP2 | P18065 | 1/20 | 0.34 |
| ▸ | IGFBP4 | P22692 | 1/20 | 0.34 |
| ▸ | IGFBP6 | P24592 | 1/20 | 0.34 |
| ▸ | IGFBP5 | P24593 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6591655 | 0.79 | MRGPRX4 (0.47) | — | |
| SCHEMBL6080475 | 0.76 | KDM4E (0.44) | KDM4EKMT2AIGFBP3ALOX15TSHR | |
| SCHEMBL6080287 | 0.76 | KDM4E (0.46) | KDM4EKMT2AIGFBP3ALOX15TSHR | |
| SCHEMBL6081171 | 0.74 | KDM4E (0.41) | KDM4EKMT2AIGFBP3ALOX15TSHR | |
| SCHEMBL9309755 | 0.73 | COMT (0.41) | KDM4EKMT2AIGFBP3ALOX15TSHR | |
| SCHEMBL6080071 | 0.73 | KDM4E (0.44) | KDM4EKMT2AKMOKDM4A | |
| SCHEMBL10215367 | 0.72 | KMO (0.38) | KDM4EKMORBP4 | |
| SCHEMBL8123552 | 0.71 | IGFBP3 (0.43) | KDM4EKMT2AASPHIGFBP3KMO | |
| SCHEMBL10215322 | 0.71 | EPRS1 (0.53) | KDM4EKMT2AASPHIGFBP3KMO | |
| SCHEMBL10215355 | 0.71 | LDHA (0.45) | KDM4EKMT2AIGFBP3KMORBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NEURO3D (FR) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183909-A1 | Compositions derived from quinoline and quinoxaline, preparation and use thereof | NQO1, NQO2, RECQL | KDM4E 1006/4885KMT2A 1384/4885ASPH 2569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.