Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGFBP3 | P17936 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | IGFBP5 | P24593 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 2/20 | 0.36 |
| ▸ | ASPH | Q12797 | 1/20 | 0.36 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.36 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8123570 | 0.81 | GPR35 (0.49) | KDM4EALOX15TSHRTDP1KMO | |
| SCHEMBL6893457 | 0.81 | NQO2 (0.41) | KDM4ETDP1MAPTLMNA | |
| SCHEMBL3328166 | 0.77 | MGAM (0.42) | IGFBP3KDM4EKMT2AALOX15TSHR | |
| SCHEMBL3333164 | 0.77 | GRM2 (0.48) | IGFBP3KDM4EKMT2AALOX15TSHR | |
| SCHEMBL3329400 | 0.77 | IGFBP5 (0.41) | IGFBP3KDM4EALOX15TSHRHIF1A | |
| SCHEMBL31550535 | 0.75 | ALOX15 (0.41) | IGFBP3KDM4EKMT2AALOX15TSHR | |
| SCHEMBL31550536 | 0.75 | ALOX15 (0.41) | IGFBP3KDM4EKMT2AALOX15TSHR | |
| SCHEMBL10717399 | 0.75 | ALOX15 (0.41) | IGFBP3KDM4EKMT2AALOX15TSHR | |
| SCHEMBL13313445 | 0.75 | ALOX15 (0.52) | IGFBP3KDM4EKMT2AALOX15TSHR | |
| SCHEMBL3332175 | 0.74 | HSD17B14 (0.42) | IGFBP3KDM4EALOX15TSHRHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000060-A1 | NOVEL COMPOUNDS | AstraZeneca UK Limited (GB) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999002528-A1 | NOVEL COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1999-01-21 | — | — | WO | disclosed |