Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 8/20 | 0.52 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.50 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.50 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.49 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.49 |
| ▸ | KDM4A | O75164 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17970865 | 0.89 | ALDH1A1 (0.64) | ALDH1A1RAB9AKMT2ACRHBPCRHR2 | |
| SCHEMBL2600488 | 0.89 | ALDH1A1 (0.64) | ALDH1A1RAB9AKMT2ACRHBPCRHR2 | |
| SCHEMBL29278814 | 0.87 | HSD11B1 (0.54) | USP2HSD11B1NCOA1NCOA3SIRT5 | |
| SCHEMBL6081062 | 0.87 | ALDH1A1 (0.57) | USP2ALDH1A1RAB9AKMT2AACHE | |
| SCHEMBL1793733 | 0.84 | HSD11B1 (0.61) | ALDH1A1RAB9AKMT2AHSD11B1ACHE | |
| SCHEMBL17970867 | 0.82 | ALDH1A1 (0.73) | USP2ALDH1A1RAB9AKMT2AHSD11B1 | |
| SCHEMBL6081660 | 0.82 | TRPA1 (0.58) | ALDH1A1RAB9AKMT2ANPSR1LMNA | |
| SCHEMBL6081489 | 0.82 | ALDH1A1 (0.73) | USP2ALDH1A1RAB9AKMT2AHSD11B1 | |
| SCHEMBL6081299 | 0.82 | ALDH1A1 (0.55) | ALDH1A1RAB9AKMT2ACRHBPCRHR2 | |
| SCHEMBL17970866 | 0.82 | ALDH1A1 (0.78) | ALDH1A1RAB9AKMT2ANPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108997215-A | A kind of preparation method of 1,2,3,4- tetrahydro isoquinoline derivative | 武汉大学 | 2018-12-14 | — | — | CN | disclosed |
| CN-104804004-B | A kind of preparation method of chiral hexahydropyrrolo diindyl class compound | 安徽师范大学 | 2017-03-29 | — | — | CN | disclosed |
| CN-105753752-A | Chiral vicinal diamine compound and method for preparing same | 安徽师范大学 | 2016-07-13 | — | — | CN | disclosed |
| CN-104804004-A | Preparation method of chiral hexahydropyrroloindole compound | UNIV ANHUI NORMAL | 2015-07-29 | — | — | CN | disclosed |
| US-20060030718-A1 | Cobalt-based catalysts for the cyclization of alkenes | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2006-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060030718-A1 | Cobalt-based catalysts for the cyclization of alkenes | PPOX, HCCS, ICOSLG | USP2 3706/4885ALDH1A1 3259/4885RAB9A 4044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.