Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10869086 | 0.85 | LMNA (0.55) | NOTUMRAB9ALMNAHTTALDH1A1 | |
| SCHEMBL68594 | 0.83 | NOTUM (0.72) | NOTUMRAB9ALMNAHTTALDH1A1 | |
| SCHEMBL23409642 | 0.80 | TSHR (0.71) | NOTUMRAB9ALMNAALDH1A1TSHR | |
| SCHEMBL28021992 | 0.78 | LMNA (0.68) | NOTUMRAB9ALMNAHTTALDH1A1 | |
| SCHEMBL25937330 | 0.78 | ALDH1A1 (0.51) | NOTUMRAB9ALMNAHTTALDH1A1 | |
| SCHEMBL9956661 | 0.76 | LMNA (0.58) | NOTUMRAB9ALMNAHTTALDH1A1 | |
| SCHEMBL642025 | 0.75 | NOTUM (0.70) | NOTUMRAB9ALMNAHTTALDH1A1 | |
| SCHEMBL25429945 | 0.75 | ALDH1A1 (0.50) | NOTUMRAB9ALMNAHTTALDH1A1 | |
| SCHEMBL842907 | 0.74 | HPGD (0.64) | NOTUMRAB9ALMNAHTTALDH1A1 | |
| SCHEMBL31562020 | 0.73 | LMNA (0.66) | NOTUMRAB9ALMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040966-A1 | ANTI-VIRAL COMPOUNDS, TREATMENT, AND ASSAY | SOUTHERN RESEARCH INSTITUTE OFFICE OF COMMERCIALIZATION AND INTELLECTUAL PROP (US) | 2012-02-16 | — | — | US | disclosed |
| EP-2381944-A1 | ANTI-VIRAL COMPOUNDS, TREATMENT, AND ASSAY | Southern Research Institute (US) | 2011-11-02 | — | — | EP | disclosed |
| WO-2010078229-A1 | ANTI-VIRAL COMPOUNDS, TREATMENT, AND ASSAY | SOUTHERN RESEARCH INSTITUTE (US) | 2010-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040966-A1 | ANTI-VIRAL COMPOUNDS, TREATMENT, AND ASSAY | ZC3HAV1, OAT, MAVS | NOTUM 1359/4885RAB9A 4055/4885LMNA 205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.