SCHEMBL60855

SCHEMBL60855

C[Si](C)(C)C[Zr](C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.35
HTR6 P50406 1/20 0.35
SIGMAR1 Q99720 6/20 0.33
KDM4E B2RXH2 2/20 0.33
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
CHRM2 P08172 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CHRM1 P11229 1/20 0.33
DRD2 P14416 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33
NFKB1 P19838 1/20 0.33
CHRM3 P20309 1/20 0.33
SLC6A2 P23975 1/20 0.33
HTR2C P28335 1/20 0.33
ADRA1A P35348 1/20 0.33
HRH1 P35367 1/20 0.33
DRD3 P35462 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4360299 0.80 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4ELMNA
SCHEMBL8734237 0.77 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4ELMNA
SCHEMBL29758162 0.74 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4ELMNA
SCHEMBL2136144 0.74 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4ELMNA
SCHEMBL6763868 0.74 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4ELMNA
SCHEMBL15863401 0.73 HTR2A (0.40) HTR2AHTR6SIGMAR1KDM4ELMNA
SCHEMBL6682538 0.73 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4ELMNA
SCHEMBL5183638 0.71 HTR2A (0.39) HTR2AHTR6SIGMAR1KDM4ELMNA
SCHEMBL5278165 0.70 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4ELMNA
SCHEMBL3798506 0.70 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3519456-B1 CAPPED MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING AND PROCESS TO PREPARE THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2024-07-03 EP disclosed
EP-3519455-B1 MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING AND PROCESS TO PREPARE THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2024-04-10 EP disclosed
EP-3596138-B1 CATALYST SYSTEM FOR MULTI-BLOCK COPOLYMER FORMATION DOW GLOBAL TECHNOLOGIES LLC (US) 2024-04-03 EP disclosed
US-11897992-B2 Catalyst system for multi-block copolymer formation DOW GLOBAL TECHNOLOGIES LLC (US) 2024-02-13 US disclosed
US-11459409-B2 Catalyst system for multi-block copolymer formation DOW GLOBAL TECHNOLOGIES LLC (US) 2022-10-04 US disclosed
US-11359038-B2 Capped multi- or dual-headed compositions useful for chain shuttling and process to prepare the same DOW GLOBAL TECHNOLOGIES LLC (US) 2022-06-14 US disclosed
US-11359035-B2 Multi- or dual-headed compositions useful for chain shuttling and process to prepare the same DOW GLOBAL TECHNOLOGIES LLC (US) 2022-06-14 US disclosed
EP-2894176-B1 Catalyst composition comprising shuttling agent for regio-irregular multi-block copolymer formation DOW GLOBAL TECHNOLOGIES LLC (US) 2022-06-01 EP disclosed
US-11208502-B2 Catalyst system for multi-block coploymer formation DOW GLOBAL TECHNOLOGIES LLC (US) 2021-12-28 US disclosed
US-11174329-B2 Multi- or dual-headed compositions useful for chain shuttling and process to prepare the same DOW GLOBAL TECHNOLOGIES LLC (US) 2021-11-16 US disclosed
WO-2001023442-A1 SUPPORTED CATALYST COMPRISING EXPANDED ANIONS THE DOW CHEMICAL COMPANY (US) 2001-04-05 WO disclosed
WO-2001004167-A1 COORDINATION POLYMERIZATION CATALYSTS COMPRISING AN ION EXCHANGE RESIN THE DOW CHEMICAL COMPANY (US) 2001-01-18 WO disclosed
EP-1066110-A1 ION EXCHANGED ALUMINIUM-MAGNESIUM SILICATE OR FLUORINATED MAGNESIUM SILICATE AEROGELS AND CATALYST SUPPORTS THEREFROM THE DOW CHEMICAL COMPANY (US) 2001-01-10 EP disclosed
EP-1000093-A1 ZWITTERIONIC CATALYST ACTIVATOR THE DOW CHEMICAL COMPANY (US) 2000-05-17 EP disclosed
EP-1000068-A1 PERFLUORONAPHTHYL SUBSTITUTED BORON CONTAINING CATALYST ACTIVATOR THE DOW CHEMICAL COMPANY (US) 2000-05-17 EP disclosed
EP-1000069-A1 CATALYST ACTIVATOR THE DOW CHEMICAL COMPANY (US) 2000-05-17 EP disclosed
WO-1999048605-A1 ION EXCHANGED ALUMINIUM-MAGNESIUM OR FLUORINATED MAGNESIUM SILICATE AEROGELS AND CATALYST SUPPORTS THEREFROM THE DOW CHEMICAL COMPANY (US) 1999-09-30 WO disclosed
WO-1999006449-A1 ZWITTERIONIC CATALYST ACTIVATOR THE DOW CHEMICAL COMPANY (US) 1999-02-11 WO disclosed
WO-1999006413-A1 CATALYST ACTIVATOR THE DOW CHEMICAL COMPANY (US) 1999-02-11 WO disclosed
WO-1999006412-A1 PERFLUORONAPHTHYL SUBSTITUTED BORON CONTAINING CATALYST ACTIVATOR THE DOW CHEMICAL COMPANY (US) 1999-02-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11174329-B2 Multi- or dual-headed compositions useful for chain shuttling and process to prepare the same ORC3, DUOX1, MCM2 HTR2A 4550/4885HTR6 4126/4885SIGMAR1 3387/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.