Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6682538 | 0.85 | HTR2A (0.38) | HTR2AHTR6SIGMAR1KDM4ELMNA | |
| SCHEMBL8734237 | 0.81 | HTR2A (0.38) | HTR2AHTR6SIGMAR1KDM4ELMNA | |
| SCHEMBL60855 | 0.80 | HTR2A (0.35) | HTR2AHTR6SIGMAR1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL7640008 | 0.79 | HTR6 (0.37) | HTR2AHTR6SIGMAR1KDM4ELMNA | |
| SCHEMBL6763868 | 0.78 | HTR2A (0.38) | HTR2AHTR6SIGMAR1KDM4ELMNA | |
| SCHEMBL29758162 | 0.78 | HTR2A (0.38) | HTR2AHTR6SIGMAR1KDM4ELMNA | |
| SCHEMBL2136144 | 0.78 | HTR2A (0.38) | HTR2AHTR6SIGMAR1KDM4ELMNA | |
| SCHEMBL15863401 | 0.77 | HTR2A (0.40) | HTR2AHTR6SIGMAR1KDM4ELMNA | |
| SCHEMBL8382871 | 0.77 | SIGMAR1 (0.37) | HTR2AHTR6SIGMAR1KDM4ELMNA | |
| SCHEMBL5183638 | 0.75 | HTR2A (0.39) | HTR2AHTR6SIGMAR1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1062219-A1 | INTEGRATED PROCESS FOR PREPARATION OF DIENE COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 2000-12-27 | — | — | EP | claimed |
| WO-1999046270-A1 | INTEGRATED PROCESS FOR PREPARATION OF DIENE COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 1999-09-16 | — | — | WO | claimed |
| US-7619106-B2 | Preparation of partially hydrogenated rac-ansa-metallocene complexes | BASELL POLYOLEFINE GMBH (DE) | 2009-11-17 | — | — | US | disclosed |
| US-20080200708-A1 | Preparation of Partially Hydrogenated Rac-Ansa-Metallocene Complexes | BASELL POLYOLEFINE GMBH (DE) | 2008-08-21 | — | — | US | disclosed |
| EP-1554295-B1 | PREPARATION OF PARTIALLY HYDROGENATED RAC-ANSA-METALLOCENE COMPLEXES | BASELL POLYOLEFINE GMBH (DE) | 2008-07-02 | — | — | EP | disclosed |
| EP-1554295-A1 | PREPARATION OF PARTIALLY HYDROGENATED RAC-ANSA-METALLOCENE COMPLEXES | Basell Polyolefine GmbH (DE) | 2005-07-20 | — | — | EP | disclosed |
| WO-2004037838-A1 | PREPARATION OF PARTIALLY HYDROGENATED RAC-ANSA-METALLOCENE COMPLEXES | BASELL POLYOLEFINE GMBH (DE) | 2004-05-06 | — | — | WO | disclosed |
| EP-1062219-A1 | INTEGRATED PROCESS FOR PREPARATION OF DIENE COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 2000-12-27 | — | — | EP | disclosed |
| WO-1999046270-A1 | INTEGRATED PROCESS FOR PREPARATION OF DIENE COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 1999-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200708-A1 | Preparation of Partially Hydrogenated Rac-Ansa-Metallocene Complexes | HRAS, RAP1A, NBAS | HTR2A 1313/4885HTR6 2018/4885SIGMAR1 1030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.