Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 3/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | PSD | A5PKW4 | 2/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.30 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10237934 | 0.74 | RAB9A (0.40) | SLC6A3ACHEHRH3KDM4EMEN1 | |
| SCHEMBL10238101 | 0.74 | TARBP2 (0.41) | SLC6A3KDM4EMEN1POLBMAPT | |
| SCHEMBL10238098 | 0.73 | NPC1 (0.39) | SLC6A3ACHEHRH2HRH3MCHR1 | |
| SCHEMBL10238015 | 0.71 | ALDH1A1 (0.40) | SLC6A3ACHEHRH3MAPK1KDM4E | |
| SCHEMBL10238001 | 0.69 | ALDH1A1 (0.39) | SLC6A3ACHEHRH3KDM4EMEN1 | |
| SCHEMBL10237969 | 0.69 | SMN1; SMN2 (0.46) | SLC6A3KDM4EMEN1POLBGAA | |
| SCHEMBL16215992 | 0.69 | HRH3 (0.41) | SLC6A3HRH3KDM4EMEN1POLB | |
| SCHEMBL608047 | 0.69 | HRH3 (0.41) | SLC6A3HRH3KDM4EMEN1POLB | |
| SCHEMBL10237937 | 0.69 | HRH3 (0.41) | SLC6A3HRH3KDM4EMEN1POLB | |
| SCHEMBL10237932 | 0.67 | PIK3CA (0.37) | ACHEPIK3CAKDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2176222-B1 | NOVEL HERBICIDES | SYNGENTA LTD (GB) | 2014-11-05 | — | — | EP | disclosed |
| US-8598365-B2 | Herbicides | SYNGENTA LIMITED (GB) | 2013-12-03 | — | — | US | disclosed |
| US-8541594-B2 | — | — | 2013-09-24 | — | — | US | disclosed |
| US-20120040826-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2012-02-16 | — | — | US | disclosed |
| EP-2176222-A1 | NOVEL HERBICIDES | Syngenta Limited (GB) | 2010-04-21 | — | — | EP | disclosed |
| WO-2009015877-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2009-02-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040826-A1 | NOVEL HERBICIDES | DDT, HDHD5, DDC | SLC6A3 858/4885ACHE 120/4885HRH2 2192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.