Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 2/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CD74 | P04233 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6086149 | 0.91 | MTNR1A (0.35) | MTNR1AMTNR1BGRIN1GRIN2BKMT2A | |
| SCHEMBL6086605 | 0.86 | HPGD (0.42) | HSD17B10KMT2AADORA3HPGDALDH1A1 | |
| SCHEMBL6086282 | 0.86 | DAO (0.45) | DAOKMT2APOLBADORA3HPGD | |
| SCHEMBL6086546 | 0.85 | TPH1 (0.34) | GRIN1GRIN2BDAOHSD17B10KMT2A | |
| SCHEMBL6087289 | 0.85 | MTNR1A (0.48) | MTNR1AMTNR1BGRIN1GRIN2BMIF | |
| SCHEMBL7837651 | 0.84 | MTNR1A (0.50) | MTNR1AMTNR1BGRIN1GRIN2BMIF | |
| SCHEMBL6087689 | 0.83 | GRIN1 (0.40) | GRIN1GRIN2BDAOKMT2APIK3R1 | |
| SCHEMBL6086822 | 0.82 | NPC1 (0.37) | GRIN1GRIN2BKMT2AADORA3HPGD | |
| SCHEMBL6086447 | 0.82 | MTNR1A (0.49) | MTNR1AMTNR1BGRIN1GRIN2BMIF | |
| SCHEMBL6086939 | 0.81 | GRIN1 (0.43) | GRIN1GRIN2BPOLBHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |