Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6086384 | 0.91 | MTNR1A (0.47) | MTNR1AMTNR1BADORA3ALDH1A1MAPT | |
| SCHEMBL6086546 | 0.90 | TPH1 (0.34) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL6086367 | 0.85 | TYMS (0.37) | MAPTHPGDMAPK1TSHR | |
| SCHEMBL6085643 | 0.85 | GRIN1 (0.36) | ALDH1A1KMT2ASMN1; SMN2GRIN1GRIN2B | |
| SCHEMBL6087279 | 0.85 | ALDH1A1 (0.33) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL6086605 | 0.84 | HPGD (0.42) | ADORA3ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6088018 | 0.84 | MTNR1A (0.36) | MTNR1AMTNR1BADORA3ALDH1A1MAPT | |
| SCHEMBL7845270 | 0.83 | MTNR1A (0.38) | MTNR1AMTNR1BALDH1A1MAPTMEN1 | |
| SCHEMBL6085665 | 0.82 | TSHR (0.34) | MAPTMEN1KMT2AHPGDTP53 | |
| SCHEMBL6086282 | 0.82 | DAO (0.45) | ADORA3ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |