Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 5/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6086605 | 0.85 | HPGD (0.42) | KMT2A | |
| SCHEMBL6087278 | 0.85 | GRIN1 (0.41) | GRIN1GRIN2BIDH1PIK3R1PIK3CA | |
| SCHEMBL7848132 | 0.84 | GRIN1 (0.40) | GRIN1GRIN2BIDH1PIK3R1PIK3CA | |
| SCHEMBL6086546 | 0.84 | TPH1 (0.34) | GRIN1GRIN2BKMT2ADAO | |
| SCHEMBL6086384 | 0.83 | MTNR1A (0.47) | GRIN1GRIN2BPIK3R1PIK3CAKMT2A | |
| SCHEMBL6086282 | 0.83 | DAO (0.45) | KMT2ADAO | |
| SCHEMBL6087882 | 0.82 | GRIN1 (0.49) | GRIN1GRIN2BDPP4 | |
| SCHEMBL6086822 | 0.81 | NPC1 (0.37) | GRIN1GRIN2BKMT2A | |
| SCHEMBL6087484 | 0.80 | GRIN1 (0.43) | GRIN1GRIN2BIDH1PIK3R1PIK3CA | |
| SCHEMBL6086939 | 0.80 | GRIN1 (0.43) | GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |