Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NAT1 | P18440 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.35 |
| ▸ | DRD1 | P21728 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6086864 | 0.87 | HPGD (0.44) | MAPTALDH1A1MAPK1KMT2AMEN1 | |
| SCHEMBL6087014 | 0.87 | DAO (0.46) | MAPTALDH1A1MAPK1KMT2AMEN1 | |
| SCHEMBL6086860 | 0.86 | ALDH1A1 (0.37) | MAPTALDH1A1SMN1; SMN2NPC1LMNA | |
| SCHEMBL6087044 | 0.84 | SMN1; SMN2 (0.37) | MAPTALDH1A1SMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL6086483 | 0.82 | MTNR1A (0.50) | ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL6086212 | 0.80 | MAPT (0.42) | MAPTALDH1A1SMN1; SMN2NPC1LMNA | |
| SCHEMBL6086881 | 0.80 | SMN1; SMN2 (0.42) | MAPTALDH1A1SMN1; SMN2NPC1LMNA | |
| SCHEMBL6087695 | 0.80 | GRIN1 (0.44) | KMT2A | |
| SCHEMBL6085671 | 0.80 | GRIN1 (0.44) | ALDH1A1MAPK1HPGD | |
| SCHEMBL6086259 | 0.79 | GRIN1 (0.37) | ALDH1A1SMN1; SMN2KMT2AHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |