Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 13/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 13/20 | 0.49 |
| ▸ | DPP4 | P27487 | 5/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6086254 | 0.85 | GRIN1 (0.50) | GRIN1GRIN2BDPP4OPRM1OPRK1 | |
| SCHEMBL6086605 | 0.83 | HPGD (0.42) | — | |
| SCHEMBL6087689 | 0.82 | GRIN1 (0.40) | GRIN1GRIN2BDPP4 | |
| SCHEMBL6086571 | 0.80 | GRIN1 (0.49) | GRIN1GRIN2BDPP4NOX4 | |
| SCHEMBL6086546 | 0.80 | TPH1 (0.34) | GRIN1GRIN2B | |
| SCHEMBL6086789 | 0.80 | GRIN1 (0.48) | GRIN1GRIN2BDPP4NOX4 | |
| SCHEMBL6086282 | 0.79 | DAO (0.45) | — | |
| SCHEMBL6088087 | 0.78 | GRIN1 (0.45) | GRIN1GRIN2BNOX4 | |
| SCHEMBL6086314 | 0.78 | HTT (0.33) | — | |
| SCHEMBL6087118 | 0.78 | ROCK2 (0.34) | GRIN1GRIN2BDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |