Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 8/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TPH1 | P17752 | 1/20 | 0.40 |
| ▸ | TPH2 | Q8IWU9 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 3/20 | 0.39 |
| ▸ | NOX4 | Q9NPH5 | 3/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7843324 | 0.93 | GRIN1 (0.41) | GRIN1GRIN2BGLATPH1TPH2 | |
| SCHEMBL6086864 | 0.85 | HPGD (0.44) | TLR7 | |
| SCHEMBL6087851 | 0.84 | GRIN1 (0.45) | GRIN1GRIN2BTPH1TPH2NOX4 | |
| SCHEMBL6086584 | 0.84 | DCTPP1 (0.34) | TPH1TPH2DRD1TLR7 | |
| SCHEMBL6087138 | 0.84 | DRD1 (0.36) | TPH1TPH2DRD1TLR7 | |
| SCHEMBL6086356 | 0.83 | PDE10A (0.42) | DRD1 | |
| SCHEMBL6085671 | 0.81 | GRIN1 (0.44) | GRIN1GRIN2BNOX4TLR7GABRA5 | |
| SCHEMBL6087044 | 0.81 | SMN1; SMN2 (0.37) | TPH1TPH2DRD1DAO | |
| SCHEMBL6088271 | 0.80 | NPBWR1 (0.35) | DRD1 | |
| SCHEMBL6087014 | 0.80 | DAO (0.46) | DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |