Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 7/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7849218 | 0.93 | GRIN1 (0.39) | GRIN1GRIN2BHPGDALDH1A1POLB | |
| SCHEMBL6086545 | 0.87 | HPGD (0.43) | HPGDALDH1A1POLBMAPK1ADORA3 | |
| SCHEMBL6087421 | 0.85 | SMN1; SMN2 (0.37) | GRIN1GRIN2BHPGDALDH1A1MAPK1 | |
| SCHEMBL6086939 | 0.84 | GRIN1 (0.43) | GRIN1GRIN2BHPGDALDH1A1POLB | |
| SCHEMBL6086507 | 0.81 | DAO (0.45) | HPGDALDH1A1MAPK1ADORA3 | |
| SCHEMBL6086609 | 0.81 | GRIN1 (0.45) | GRIN1GRIN2BMAPK1TLR7GABRA1 | |
| SCHEMBL6085656 | 0.81 | SMN1; SMN2 (0.33) | HPGDALDH1A1MAPK1ADORA3PKM | |
| SCHEMBL6086770 | 0.81 | GRIN1 (0.37) | GRIN1GRIN2BALDH1A1PKM | |
| SCHEMBL6088055 | 0.81 | TYMS (0.38) | HPGDMAPK1PKM | |
| SCHEMBL6087289 | 0.80 | MTNR1A (0.48) | GRIN1GRIN2BHPGDPOLBADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |