Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6086864 | 0.85 | HPGD (0.44) | KDM4EGAAHPGDHTTMEN1 | |
| SCHEMBL6088257 | 0.85 | NPBWR1 (0.34) | NPBWR1KDM4EGAAHPGDHTT | |
| SCHEMBL6087014 | 0.85 | DAO (0.46) | KDM4EGAAHPGDHTTMEN1 | |
| SCHEMBL6087044 | 0.82 | SMN1; SMN2 (0.37) | KDM4EGAAHPGDHTTMEN1 | |
| SCHEMBL6086356 | 0.82 | PDE10A (0.42) | KDM4EDRD1ALDH1A1PDE10ACYP1A2 | |
| SCHEMBL6088051 | 0.80 | GRIN1 (0.45) | DRD1 | |
| SCHEMBL7850946 | 0.79 | NPBWR1 (0.31) | NPBWR1KDM4EALDH1A1 | |
| SCHEMBL6088668 | 0.79 | POLB (0.35) | KDM4EGAAHTTMEN1TSHR | |
| SCHEMBL6086483 | 0.79 | MTNR1A (0.50) | MEN1TSHRKMT2AALDH1A1POLB | |
| SCHEMBL6086995 | 0.79 | POLB (0.35) | KDM4EGAAHPGDHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |