Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TACR3 | P29371 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6086928 | 0.78 | ALDH1A1 (0.50) | ALDH1A1HSD17B10MEN1KMT2AALOX15 | |
| SCHEMBL6107295 | 0.76 | ALDH1A1 (0.44) | ALDH1A1HSD17B10MEN1KMT2AALOX15 | |
| SCHEMBL2090279 | 0.70 | CYP1A2 (0.58) | ALDH1A1HSD17B10MEN1KMT2AALOX15 | |
| SCHEMBL18024095 | 0.70 | ALDH1A1 (0.54) | ALDH1A1HSD17B10MEN1KMT2AALOX15 | |
| SCHEMBL7557552 | 0.69 | CYP1A2 (0.56) | ALDH1A1HSD17B10MEN1KMT2AALOX15 | |
| SCHEMBL7410024 | 0.68 | CYP1A2 (0.55) | ALDH1A1HSD17B10MEN1KMT2AALOX15 | |
| SCHEMBL7254155 | 0.68 | ALDH1A1 (0.54) | ALDH1A1HSD17B10MEN1KMT2AALOX15 | |
| SCHEMBL3826494 | 0.67 | CYP1A2 (0.47) | ALDH1A1HSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10715095 | 0.66 | NLRP3 (0.54) | ALDH1A1HSD17B10MEN1KMT2AALOX15 | |
| SCHEMBL29648996 | 0.66 | NLRP3 (0.54) | ALDH1A1HSD17B10MEN1KMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7053108-B2 | Indoline compounds | LES LABORATOIRES SERVIER (FR) | 2006-05-30 | — | — | US | disclosed |
| US-20040192736-A1 | New indoline compounds | LAVIELLE GILBERT (FR) | 2004-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192736-A1 | New indoline compounds | TPH1, HTR3A, HTR1D | ALDH1A1 643/4885HSD17B10 500/4885MEN1 1004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.