Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TPH1 | P17752 | 1/20 | 0.32 |
| ▸ | TPH2 | Q8IWU9 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6087421 | 0.92 | SMN1; SMN2 (0.37) | SMN1; SMN2TPH1TPH2TSHRHPGD | |
| SCHEMBL6085656 | 0.89 | SMN1; SMN2 (0.33) | TYMSSMN1; SMN2TPH1TPH2TSHR | |
| SCHEMBL6086770 | 0.86 | GRIN1 (0.37) | SMN1; SMN2TPH1TPH2PKMKMT2A | |
| SCHEMBL6086545 | 0.86 | HPGD (0.43) | TPH1TPH2TSHRHPGDMAPK1 | |
| SCHEMBL6088018 | 0.84 | MTNR1A (0.36) | TYMSSMN1; SMN2LMNATSHRHPGD | |
| SCHEMBL6086917 | 0.84 | TSHR (0.34) | SMN1; SMN2TPH1TPH2TSHRHPGD | |
| SCHEMBL7854341 | 0.84 | TPH1 (0.33) | SMN1; SMN2TPH1TPH2TSHRHPGD | |
| SCHEMBL6086367 | 0.83 | TYMS (0.37) | TYMSTSHRHPGDL3MBTL1MAPK1 | |
| SCHEMBL7855333 | 0.81 | NR3C1 (0.35) | SMN1; SMN2TSHRHPGDMAPK1MEN1 | |
| SCHEMBL6086507 | 0.81 | DAO (0.45) | SMN1; SMN2TSHRHPGDMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |
| EP-1100786-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000061564-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |