Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BRD2 | P25440 | 1/20 | 0.33 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.33 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TPH1 | P17752 | 1/20 | 0.32 |
| ▸ | TPH2 | Q8IWU9 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7855333 | 0.92 | NR3C1 (0.35) | SMN1; SMN2MEN1TSHRKMT2AMAPK1 | |
| SCHEMBL6087421 | 0.92 | SMN1; SMN2 (0.37) | SMN1; SMN2PKMMEN1TSHRKMT2A | |
| SCHEMBL6088055 | 0.89 | TYMS (0.38) | SMN1; SMN2TYMSPKMMEN1TSHR | |
| SCHEMBL6086545 | 0.88 | HPGD (0.43) | BRD4MEN1TSHRKMT2AMAPK1 | |
| SCHEMBL6086770 | 0.86 | GRIN1 (0.37) | SMN1; SMN2PKMKMT2ATPH1TPH2 | |
| SCHEMBL6088018 | 0.84 | MTNR1A (0.36) | SMN1; SMN2DHFRTYMSMEN1TSHR | |
| SCHEMBL7854341 | 0.84 | TPH1 (0.33) | SMN1; SMN2MEN1TSHRKMT2AMAPK1 | |
| SCHEMBL6086917 | 0.84 | TSHR (0.34) | SMN1; SMN2MEN1TSHRKMT2AKDM4E | |
| SCHEMBL6087279 | 0.83 | ALDH1A1 (0.33) | SMN1; SMN2BRD4BRD2BRD3BRDT | |
| SCHEMBL6087645 | 0.81 | GRIN1 (0.44) | PKMMAPK1HPGDALDH1A1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |